Document Detail


Suitability of the rabbit for hypothyroid studies.
MedLine Citation:
PMID:  451355     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
New Zealand white rabbits were thyroidectomized, then examined for hypothyroidism after 6 to 8 weeks. Serum thyroxine levels were reduced 77% after surgery. This occurred without apparent calcium homeostatic imbalances even though no calcium supplementation was added to the food or water. The advantages of using the animal and procedure are discussed.
Authors:
J E Holl; L S Howard
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Research communications in chemical pathology and pharmacology     Volume:  25     ISSN:  0034-5164     ISO Abbreviation:  Res. Commun. Chem. Pathol. Pharmacol.     Publication Date:  1979 Jul 
Date Detail:
Created Date:  1979-09-01     Completed Date:  1979-09-01     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0244734     Medline TA:  Res Commun Chem Pathol Pharmacol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  185-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Body Temperature
Disease Models, Animal*
Female
Hypothyroidism / physiopathology*
Male
Methods
Rabbits / physiology*
Thyroidectomy
Thyroxine / blood
Chemical
Reg. No./Substance:
7488-70-2/Thyroxine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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