| Suitability of bupropion SR for nicotine-dependent smokers: problems in a practice setting. | |
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MedLine Citation:
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PMID: 15184720 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Bupropion SR (Zyban) has been shown in randomized controlled trials to be an efficacious pharmacological aid for smoking cessation; however, recent reports have raised serious concerns about the breadth of its applicability without complications or contraindications. METHODS: We examined this issue in a well-documented medical population, i.e. veterans volunteering to participate in a smoking cessation treatment research program involving the use of bupropion SR. RESULTS: Overall, 22% of the 78 subjects who met the study criteria were appropriate for and completed the course of medication. CONCLUSIONS: Thus, bupropion SR in nicotine-dependent veterans may not be broadly applicable when conservative prescribing guidelines are carefully followed. |
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Authors:
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Barbara S Kohlenberg; David O Antonuccio; Steven C Hayes; Elizabeth V Gifford; Melissa P Piasecki |
Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Psychotherapy and psychosomatics Volume: 73 ISSN: 0033-3190 ISO Abbreviation: Psychother Psychosom Publication Date: 2004 Jul-Aug |
Date Detail:
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Created Date: 2004-06-08 Completed Date: 2004-10-05 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0024046 Medline TA: Psychother Psychosom Country: Switzerland |
Other Details:
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Languages: eng Pagination: 252-4 Citation Subset: IM |
Copyright Information:
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Copyright 2004 S. Karger AG, Basel |
Affiliation:
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VA Sierra Nevada Health Care System, Reno, NV, USA. Barbarak@unr.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Bupropion / contraindications, therapeutic use* Dopamine Uptake Inhibitors / therapeutic use* Female Humans Male Middle Aged Smoking Cessation / methods* Tobacco Use Disorder / drug therapy* |
| Grant Support | |
ID/Acronym/Agency:
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1R01DA13106-01/DA/NIDA NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Dopamine Uptake Inhibitors; 34841-39-9/Bupropion |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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