Document Detail

Suicide and patients with neurologic diseases. Methodologic problems.
MedLine Citation:
PMID:  1449409     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The suicide risk in patients with many neurologic diseases has been reported to be greater than that in the general population. Studies on the subject are, however, often encumbered with methodologic problems. We appraised these problems and, based on an evaluation, reappraised knowledge of the suicide risk in patients with specific neurologic diseases. DATA SOURCE: Using the computerized database MEDLINE, we identified all published reports with the key words suicide, attempted suicide, and neurologic diseases. STUDY SELECTION: We assessed and reviewed studies concerning the most common neurologic diseases for methodologic problems in the study design. DATA EXTRACTION: The following methodologic problems emerged during our review: (1) choice of study type, ie, autopsy study or follow-up study; (2) choice of study population; (3) choice of control groups; (4) epidemiologic/statistical methods used; and (5) validity of statistics reported. DATA SYNTHESIS: We analyzed the methodologic problems in studies of patients with multiple sclerosis, epilepsy, Huntington's chorea, spinal cord lesions, cranial trauma, brain tumors, Parkinson's disease, vascular disorders, and migraine. In most of the studies, the methods used gave rise to uncertainty about the conclusion presented. CONCLUSION: An increased suicide risk was found in patients suffering from multiple sclerosis and spinal cord lesions as well as in selected groups of patients with epilepsy. In other neurologic diseases, the suicide risk may be increased, but the results are uncertain due to the methodologic problems in the study design.
E N Stenager; E Stenager
Related Documents :
15623669 - Identifying and treating patients with suboptimal responses.
18598229 - Cerebrospinal fluid biomarkers of neurodegeneration in chronic neurological diseases.
25481609 - Poncet's disease (tubercular rheumatism) - a case report.
16967489 - Predictability of disease progression in amyotrophic lateral sclerosis.
17282989 - Myelin repair: the role of stem and precursor cells in multiple sclerosis.
18061279 - Bdnf a196g and c270t gene polymorphisms and susceptibility to multiple sclerosis in the...
15623669 - Identifying and treating patients with suboptimal responses.
18250089 - Associated factors and impact of myocarditis in patients with sle from lumina, a multie...
10342749 - Endogenous neutralizing anti-il-1 alpha autoantibodies in inflammatory skin diseases: p...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Archives of neurology     Volume:  49     ISSN:  0003-9942     ISO Abbreviation:  Arch. Neurol.     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1992-12-30     Completed Date:  1992-12-30     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  0372436     Medline TA:  Arch Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1296-303     Citation Subset:  AIM; IM    
Department of Psychiatry, Odense University, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Brain Injuries / complications,  psychology
Brain Neoplasms / complications,  psychology
Epilepsy / complications,  psychology
Huntington Disease / psychology
Migraine Disorders / complications,  psychology
Multiple Sclerosis / complications,  psychology
Nervous System Diseases / complications*,  psychology
Parkinson Disease / complications,  psychology
Spinal Cord Injuries / complications,  psychology
Suicide, Attempted

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Frontal lobe dysfunction in unilateral lenticulostriate infarcts. Prominent role of cortical lesions...
Next Document:  Effect of ethanol on mouse brain microsomal phospholipid turnover.