| Suicide in patients treated for obsessive-compulsive disorder: a prospective follow-up study. | |
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MedLine Citation:
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PMID: 20060171 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: To describe the occurrence of persistent suicidal ideation and suicide attempts in a sample of obsessive-compulsive patients followed-up prospectively during 1 to 6years, and to determine the existence of predictors of suicide behavior. METHOD: Two hundred and eighteen outpatients with DSM-IV OCD, recruited from a specialized OCD Unit in Barcelona, Spain, between February 1998 and December 2007, were included in the study. Suicide ideation was assessed by item 3 of the Hamilton Depression Rating Scale. Suicide attempts were evaluated by the Beck Suicide Intent Scale. Patients with and without persistent suicidal thoughts and suicide attempters and non-attempters were compared on sociodemographic and clinical variables. A Cox proportional hazards regression analysis was used to estimate potential predictors of suicide. RESULTS: Patients completed a mean follow-up period of treatment of 4.1years (SD: 1.7; range: 1-6years). During this period, eighteen patients (8.2%) reported persistent suicidal ideation, two patients (0.91%) committed suicide and 11 (5.0%) attempted suicide. Being unmarried, presenting higher basal scores in the HDRS, current or previous history of affective disorders and symmetry/ordering obsessions were independently associated with suicidal behaviors. LIMITATIONS: Patients were recruited from a specialized OCD clinic and received exhaustive treatment. Influence of variables including social support, life events, hopelessness and substance abuse/dependence was not assessed. CONCLUSIONS: Suicide behavior is not a highly common phenomenon in OCD, but it should not be disregarded, especially in unmarried patients, with comorbid depression and symmetry/ordering obsessions and compulsions, who appear to be at a greater risk for suicide acts. |
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Authors:
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P Alonso; C Segalàs; E Real; A Pertusa; J Labad; S Jiménez-Murcia; N Jaurrieta; B Bueno; J Vallejo; J M Menchón |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-01-13 |
Journal Detail:
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Title: Journal of affective disorders Volume: 124 ISSN: 1573-2517 ISO Abbreviation: J Affect Disord Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-12 Completed Date: 2010-10-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7906073 Medline TA: J Affect Disord Country: Netherlands |
Other Details:
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Languages: eng Pagination: 300-8 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier B.V. All rights reserved. |
Affiliation:
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OCD Clinical and Research Unit, Department of Psychiatry, Bellvitge University Hospital, 08907 L'Hospitalet de Llobregat, Barcelona, Spain. mpalonso@bellvitgehospital.cat |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Cognitive Therapy Combined Modality Therapy Comorbidity Female Follow-Up Studies Humans Male Middle Aged Mood Disorders / epidemiology, psychology, therapy Obsessive-Compulsive Disorder / epidemiology, psychology*, therapy* Personality Disorders / epidemiology, psychology, therapy Personality Inventory / statistics & numerical data Prospective Studies Psychometrics Risk Factors Serotonin Uptake Inhibitors / therapeutic use Suicide / psychology*, statistics & numerical data* Suicide, Attempted / psychology*, statistics & numerical data* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Serotonin Uptake Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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