Document Detail


Suicide in patients treated for obsessive-compulsive disorder: a prospective follow-up study.
MedLine Citation:
PMID:  20060171     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: To describe the occurrence of persistent suicidal ideation and suicide attempts in a sample of obsessive-compulsive patients followed-up prospectively during 1 to 6years, and to determine the existence of predictors of suicide behavior. METHOD: Two hundred and eighteen outpatients with DSM-IV OCD, recruited from a specialized OCD Unit in Barcelona, Spain, between February 1998 and December 2007, were included in the study. Suicide ideation was assessed by item 3 of the Hamilton Depression Rating Scale. Suicide attempts were evaluated by the Beck Suicide Intent Scale. Patients with and without persistent suicidal thoughts and suicide attempters and non-attempters were compared on sociodemographic and clinical variables. A Cox proportional hazards regression analysis was used to estimate potential predictors of suicide. RESULTS: Patients completed a mean follow-up period of treatment of 4.1years (SD: 1.7; range: 1-6years). During this period, eighteen patients (8.2%) reported persistent suicidal ideation, two patients (0.91%) committed suicide and 11 (5.0%) attempted suicide. Being unmarried, presenting higher basal scores in the HDRS, current or previous history of affective disorders and symmetry/ordering obsessions were independently associated with suicidal behaviors. LIMITATIONS: Patients were recruited from a specialized OCD clinic and received exhaustive treatment. Influence of variables including social support, life events, hopelessness and substance abuse/dependence was not assessed. CONCLUSIONS: Suicide behavior is not a highly common phenomenon in OCD, but it should not be disregarded, especially in unmarried patients, with comorbid depression and symmetry/ordering obsessions and compulsions, who appear to be at a greater risk for suicide acts.
Authors:
P Alonso; C Segalàs; E Real; A Pertusa; J Labad; S Jiménez-Murcia; N Jaurrieta; B Bueno; J Vallejo; J M Menchón
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-01-13
Journal Detail:
Title:  Journal of affective disorders     Volume:  124     ISSN:  1573-2517     ISO Abbreviation:  J Affect Disord     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-10-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7906073     Medline TA:  J Affect Disord     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  300-8     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier B.V. All rights reserved.
Affiliation:
OCD Clinical and Research Unit, Department of Psychiatry, Bellvitge University Hospital, 08907 L'Hospitalet de Llobregat, Barcelona, Spain. mpalonso@bellvitgehospital.cat
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cognitive Therapy
Combined Modality Therapy
Comorbidity
Female
Follow-Up Studies
Humans
Male
Middle Aged
Mood Disorders / epidemiology,  psychology,  therapy
Obsessive-Compulsive Disorder / epidemiology,  psychology*,  therapy*
Personality Disorders / epidemiology,  psychology,  therapy
Personality Inventory / statistics & numerical data
Prospective Studies
Psychometrics
Risk Factors
Serotonin Uptake Inhibitors / therapeutic use
Suicide / psychology*,  statistics & numerical data*
Suicide, Attempted / psychology*,  statistics & numerical data*
Young Adult
Chemical
Reg. No./Substance:
0/Serotonin Uptake Inhibitors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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