Document Detail


Sugars and alcohol: IgA-associated renal diseases in alcoholic cirrhosis.
MedLine Citation:
PMID:  22126980     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Tissandié and colleagues report in this issue on their studies of IgA1 glycosylation and biological activities of IgA1-containing circulating immune complexes in patients with alcoholic cirrhosis who developed secondary renal disease with IgA deposits, secondary IgA nephropathy. Their seminal findings demonstrate abnormal glycosylation of IgA1 N-linked as well as O-linked glycans. Furthermore, their work reveals unique biological properties of immune complexes in these patients as compared with those in patients with primary IgA nephropathy.
Authors:
Jan Novak; Bruce A Julian
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Kidney international     Volume:  80     ISSN:  1523-1755     ISO Abbreviation:  Kidney Int.     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0323470     Medline TA:  Kidney Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1252-4     Citation Subset:  IM    
Affiliation:
Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
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