Document Detail

Sugar is not an aggravating factor in atopic dermatitis.
MedLine Citation:
PMID:  11720177     Owner:  NLM     Status:  MEDLINE    
Patients with atopic dermatitis frequently blame food for worsening their eczema. Recently, a sugar-free diet has become very popular among German patients. In order to investigate whether sucrose is an aggravating factor in atopic dermatitis, we conducted a prospective study in 30 patients. Double-blind, placebo-controlled food challenges with sugar were performed during a sugar-free diet period, which was started one week prior to the first challenge. Study parameters included the SCORAD index and eosinophilic cationic protein levels, which were determined before diet, on food challenges and one day after. In 29 evaluable patients we observed no significant difference in study parameters after the verum challenge compared to the placebo challenge. From these results, we conclude that sugar is not an aggravating factor in atopic dermatitis, which contradicts the view of many patients and underlines the importance of evidence-based medicine in the guidance of patients.
I Ehlers; M Worm; W Sterry; T Zuberbier
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  81     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:    2001 Aug-Sep
Date Detail:
Created Date:  2001-11-26     Completed Date:  2002-04-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  282-4     Citation Subset:  IM    
Department of Dermatology and Allergy, Charité, Humboldt-University, Berlin, Germany.
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MeSH Terms
Child, Preschool
Dermatitis, Atopic / chemically induced,  diet therapy*
Dietary Sucrose / adverse effects*
Double-Blind Method
Evidence-Based Medicine
Middle Aged
Prospective Studies
Reg. No./Substance:
0/Dietary Sucrose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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