| Sugar cane policosanol failed to lower plasma cholesterol in primitive, diet-resistant hypercholesterolaemia: a double blind, controlled study. | |
| | |
MedLine Citation:
|
PMID: 18514906 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Previous clinical studies have shown that oral administration of sugar cane policosanol (SCP) reduces plasma total cholesterol and low-density lipoprotein cholesterol levels. A double blind, randomized, placebo controlled trial was performed in hypercholesterolaemic, diet-resistant patients. Seventy patients meeting the selection criteria were enrolled. Each subject was treated with policosanol 10 mg/d in addition to a dietetic regimen for 8 weeks. At the start and at the end of the study body weight, body mass index (BMI), total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides (TG) plasma levels were measured. Thirty-three subjects in the policosanol and Thirty-one subjects in the control group completed the study. During the study body mass index, total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides plasma levels did not change significantly within and between groups. In conclusion, sugar cane policosanol at a dose of 10mg/d showed no lipid lowering effects in subjects with primitive, diet-resistant hypercholesterolaemia. |
| | |
Authors:
|
F Francini-Pesenti; F Brocadello; D Beltramolli; M Nardi; L Caregaro |
Related Documents
:
|
19301686 - Control of lipids at baseline in the bypass angioplasty revascularization investigation... 4075696 - Quantitative determination of free cholesterol and cholesteryl esters in skin biopsies. 1640036 - Prediction of plasma lipids in a cross-sectional sample of young women. 12027236 - A free fatty acid tolerance test identifies patients with coronary artery disease among... 7928756 - Influence of dietary lysine on growth and carcass composition of high-lean-growth gilts... 6408496 - Small intestinal dipeptidases and disaccharidases in uraemic rats on a low protein diet. |
Publication Detail:
|
Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2008-01-18 |
Journal Detail:
|
Title: Complementary therapies in medicine Volume: 16 ISSN: 0965-2299 ISO Abbreviation: Complement Ther Med Publication Date: 2008 Apr |
Date Detail:
|
Created Date: 2008-06-02 Completed Date: 2008-08-22 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9308777 Medline TA: Complement Ther Med Country: Scotland |
Other Details:
|
Languages: eng Pagination: 61-5 Citation Subset: IM |
Affiliation:
|
Clinical Nutrition Unit, Department of Clinical and Experimental Medicine, Azienda Ospedaliera, via Giustiniani 2, 35100 Padua, Italy. francescofrancini@yahoo.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anticholesteremic Agents
/
therapeutic use* Body Mass Index Body Weight Cholesterol / blood Complementary Therapies Diet Double-Blind Method Fatty Alcohols / therapeutic use* Female Humans Hypercholesterolemia / drug therapy* Male Middle Aged Saccharum* Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
|
0/Anticholesteremic Agents; 0/Fatty Alcohols; 0/Triglycerides; 142583-61-7/policosanol; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A mass budget of polybrominated diphenyl ethers in San Francisco Bay, CA.
Next Document: Nettle sting for chronic knee pain: a randomised controlled pilot study.