| Sudomotor dysfunction in amyotrophic lateral sclerosis. | |
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MedLine Citation:
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PMID: 7883205 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We performed a quantitative sudomotor function test on 11 patients with classic amyotrophic lateral sclerosis (ALS) and 11 age-matched control subjects. Thermal warming increased the sweat rate in the forearm of ALS patients and in the forearm and thigh of control subjects. The sweat rate in the thigh of ALS patients was lower than that of controls. Thyrotropin releasing hormone increased the sweat rate in the forearm and thigh and decreased oral temperature in both ALS and controls but the lower extremity response was reduced in ALS. Results of the sudomotor axon reflex test on the thigh indicate that in ALS, there is mild postganglionic sudomotor dysfunction. We conclude that patients with ALS have mild thermoregulatory sweat dysfunction due to postganglionic lesions in the lower extremities. |
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Authors:
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M Kihara; A Takahashi; J Sugenoya; Y Kihara; H Watanabe |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Functional neurology Volume: 9 ISSN: 0393-5264 ISO Abbreviation: Funct. Neurol. Publication Date: 1994 Jul-Aug |
Date Detail:
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Created Date: 1995-04-12 Completed Date: 1995-04-12 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8707746 Medline TA: Funct Neurol Country: ITALY |
Other Details:
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Languages: eng Pagination: 193-7 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Daini Hospital, Tokyo Women's Medical College, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amyotrophic Lateral Sclerosis
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physiopathology* Autonomic Fibers, Postganglionic / physiopathology Autonomic Nervous System / physiopathology* Axons / physiology Body Temperature Regulation / physiology Female Humans Male Middle Aged Nicotine / diagnostic use Reflex / physiology Skin Temperature / physiology* Sweating / physiology* Thyrotropin-Releasing Hormone / diagnostic use |
| Chemical | |
Reg. No./Substance:
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24305-27-9/Thyrotropin-Releasing Hormone; 54-11-5/Nicotine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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