Document Detail

Sudden unexpected sneezing during the insertion of peribulbar block under propofol sedation.
MedLine Citation:
PMID:  7586116     Owner:  NLM     Status:  MEDLINE    
The author presents a case report where, following propofol sedation for a peribulbar block, sneezing was induced once the local anaesthetic needle was placed in the orbital cavity. The physiology of sneezing is discussed, as well as the pathophysiology of the ACHOO (Autosomal Dominant Compelling Helio-Ophthalmic Outburst) syndrome, an autosomal dominant condition, present in approximately 25% of the population, where sneezing is provoked upon exposure to bright light. It is suggested that the anaesthesia induced by propofol may have sensitized patients with this condition to sneeze, since there appeared to be no other excitatory sequelae which have previously been described with propofol.
D C Abramson
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Canadian journal of anaesthesia = Journal canadien d'anesthésie     Volume:  42     ISSN:  0832-610X     ISO Abbreviation:  Can J Anaesth     Publication Date:  1995 Aug 
Date Detail:
Created Date:  1995-12-04     Completed Date:  1995-12-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701709     Medline TA:  Can J Anaesth     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  740-3     Citation Subset:  IM    
Department of Anesthesiology, University of Texas Houston 77030, USA.
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MeSH Terms
Anesthetics, Intravenous / administration & dosage*,  adverse effects
Anesthetics, Local / administration & dosage
Bupivacaine / administration & dosage
Genes, Dominant
Lidocaine / administration & dosage
Nerve Block* / instrumentation
Photic Stimulation
Propofol / administration & dosage*,  adverse effects
Reflex / genetics
Sneezing / drug effects*,  genetics
Reg. No./Substance:
0/Anesthetics, Intravenous; 0/Anesthetics, Local; 137-58-6/Lidocaine; 2078-54-8/Propofol; 2180-92-9/Bupivacaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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