| Sudden unexpected death in infants under 3 months of age and vaccination status- -a case-control study. | |
| | |
MedLine Citation:
|
PMID: 11298074 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
AIMS: To determine whether DTPP+Hib vaccination (diphtheria, tetanus, pertussis, poliomyelitis +/- haemophilus) increased the risk of sudden unexpected death (SUD) in children under 3 months of age. METHODS: We conducted a multicentre case-control study in the 28 French 'SIDS Centers'. Case selection was based on death labelled sudden infant death syndrome (SIDS) of an infant aged between 30 and 90 days. Three living controls were selected, matched for sex, gestational age and born immediately after the victim in the same maternity unit. RESULTS: We identified 114 cases of SUD aged between 30 and 90 days and 341 live controls matched for age and sex and born in the same maternity unit as the case. DTPP+/-Hib immunization did not increase the risk of SUD (OR 1.08) (95% CI 0.49, 2.36) in children under 3 months of age when adjusted for sleeping position, illness in the week before death, maternal tobacco consumption, birth weight, type of mattress, breastfeeding and sex. However, low birth-weight (6.53 [2.29, 18.9]), multiple birth (5.1 [1.76, 15.13]), no breastfeeding (1.77 [1.1, 2.85]), prone sleeping position (9.8 [5, 8, 18, 9]), soft mattress (3.26 [1.69, 6.29]), recent illness (3.44 [1.84, 6.41]) and parental smoking (1.74 [1.2, 2.96]) were confirmed as risk factors in early SIDS. CONCLUSIONS: DTPP+/-Hib immunization is not a risk factor for early SUD. In this population, we found the same risk factors as described for SIDS. |
| | |
Authors:
|
A P Jonville-Béra; E Autret-Leca; F Barbeillon; J Paris-Llado; |
Related Documents
:
|
12801104 - Snoring in infancy. 6546344 - A necropsy study of distribution of petechiae in non-sudden infant death syndrome. 19826174 - Hazardous cosleeping environments and risk factors amenable to change: case-control stu... 1738324 - Climatic temperature and variation in the incidence of sudden infant death syndrome bet... 1727964 - Chronic chlamydia trachomatis infections in infants. 17333184 - Clinical examination versus ultrasonography in detecting developmental dysplasia of the... |
Publication Detail:
|
Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: British journal of clinical pharmacology Volume: 51 ISSN: 0306-5251 ISO Abbreviation: Br J Clin Pharmacol Publication Date: 2001 Mar |
Date Detail:
|
Created Date: 2001-04-12 Completed Date: 2001-05-24 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 7503323 Medline TA: Br J Clin Pharmacol Country: England |
Other Details:
|
Languages: eng Pagination: 271-6 Citation Subset: IM |
Affiliation:
|
Department of Clinical Pharmacology and Regional Drug Monitoring Center University Hospital of Tours, France. Unité Inserm U 149 Cochin Port Royal University Hospital, Paris, France. jonville-bera@chu-tours.fr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Bacterial Capsules Case-Control Studies Causality Diphtheria Toxoid* / adverse effects Diphtheria-Tetanus-Pertussis Vaccine* / adverse effects Female Haemophilus Vaccines* / adverse effects Humans Infant Male Pertussis Vaccine* / adverse effects Poliovirus Vaccine, Inactivated* / adverse effects Polysaccharides, Bacterial* / adverse effects Risk Assessment Risk Factors Sudden Infant Death / epidemiology*, etiology, immunology Tetanus Toxoid* / adverse effects Vaccines, Combined* / adverse effects |
| Chemical | |
Reg. No./Substance:
|
0/Bacterial Capsules; 0/DTPP vaccine; 0/Diphtheria Toxoid; 0/Diphtheria-Tetanus-Pertussis Vaccine; 0/Haemophilus Vaccines; 0/Haemophilus influenzae type b polysaccharide vaccine; 0/Pertussis Vaccine; 0/Poliovirus Vaccine, Inactivated; 0/Polysaccharides, Bacterial; 0/Tetanus Toxoid; 0/Vaccines, Combined |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Patterns of prescription and drug use in ophthalmology in a tertiary hospital in Delhi.
Next Document: Frequency of cytochrome P450 2C9 mutant alleles in a Korean population.