| Sudden onset of Chiari malformation Type I in previously asymptomatic patients. | |
| | |
MedLine Citation:
|
PMID: 22044365 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Chiari malformation Type I (CM-I) is usually suspected in patients with slowly progressing neurological symptoms. However, in some instances, especially if syringomyelia is associated, an abrupt clinical onset is reported and is accompanied by an acknowledged risk of potentially severe clinical signs or even sudden death. Little is known about such a critical course in CM-I/syringomyelia complex. The authors describe 3 challenging cases of the abrupt onset of CM-I/syringomyelia to reveal more information on the clinical presentation and pathogenetic mechanisms of this sudden and potentially severe clinical phenomenon: a 38-year-old man experienced acute respiratory failure requiring intubation following acute decompensation of hydrocephalus associated with Noonan syndrome, a 1-year-old boy had sudden hemiparesis and Horner syndrome after a minor head/neck injury, and a 2.5-year-old boy presented with quickly progressing tetraplegia and dyspnea after a mild flexion and extension neck injury a few hours before. All 3 patients showed a CM-I/syringomyelia complex at diagnosis, and all of them had a good neurological outcome after surgery despite the ominous clinical presentation. |
| | |
Authors:
|
Luca Massimi; Giuseppe Maria Della Pepa; Gianpiero Tamburrini; Concezio Di Rocco |
Related Documents
:
|
17484465 - Xenograft calcification in reiter's syndrome. 18084245 - Aberrant fibrillin-1 expression in early emphysematous human lung: a proposed predispos... 11208245 - Therapeutic management of patients with marfan syndrome: focus on cardiovascular involv... 1344755 - Congenital marfan syndrome with contractures. a clinicopathological report. 12712065 - Evidence for genetic heterogeneity in lymphedema-cholestasis syndrome. 15516435 - Prenatal ultrasound diagnosis of poland syndrome. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of neurosurgery. Pediatrics Volume: 8 ISSN: 1933-0715 ISO Abbreviation: J Neurosurg Pediatr Publication Date: 2011 Nov |
Date Detail:
|
Created Date: 2011-11-02 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101463759 Medline TA: J Neurosurg Pediatr Country: United States |
Other Details:
|
Languages: eng Pagination: 438-42 Citation Subset: IM |
Affiliation:
|
Department of Neurosciences, Institute of Neurosurgery, A. Gemelli Hospital, Rome, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Treatment practices for Chiari malformation Type I with syringomyelia: results of a survey of the Am...
Next Document: Unreliability of intraoperative estimated blood loss in extended sagittal synostectomies.