Document Detail

Sudden infant death syndrome.
MedLine Citation:
PMID:  17980736     Owner:  NLM     Status:  MEDLINE    
Despite declines in prevalence during the past two decades, sudden infant death syndrome (SIDS) continues to be the leading cause of death for infants aged between 1 month and 1 year in developed countries. Behavioural risk factors identified in epidemiological studies include prone and side positions for infant sleep, smoke exposure, soft bedding and sleep surfaces, and overheating. Evidence also suggests that pacifier use at sleep time and room sharing without bed sharing are associated with decreased risk of SIDS. Although the cause of SIDS is unknown, immature cardiorespiratory autonomic control and failure of arousal responsiveness from sleep are important factors. Gene polymorphisms relating to serotonin transport and autonomic nervous system development might make affected infants more vulnerable to SIDS. Campaigns for risk reduction have helped to reduce SIDS incidence by 50-90%. However, to reduce the incidence even further, greater strides must be made in reducing prenatal smoke exposure and implementing other recommended infant care practices. Continued research is needed to identify the pathophysiological basis of SIDS.
Rachel Y Moon; Rosemary S C Horne; Fern R Hauck
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Lancet     Volume:  370     ISSN:  1474-547X     ISO Abbreviation:  Lancet     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-11-05     Completed Date:  2007-11-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  England    
Other Details:
Languages:  eng     Pagination:  1578-87     Citation Subset:  AIM; IM    
Goldberg Center for Community Pediatric Health, Children's National Medical Center and George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA.
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MeSH Terms
Breast Feeding
Prenatal Exposure Delayed Effects*
Risk Factors
Sudden Infant Death* / epidemiology,  genetics,  prevention & control

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