Document Detail


Sudden infant death syndrome.
MedLine Citation:
PMID:  17980736     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Despite declines in prevalence during the past two decades, sudden infant death syndrome (SIDS) continues to be the leading cause of death for infants aged between 1 month and 1 year in developed countries. Behavioural risk factors identified in epidemiological studies include prone and side positions for infant sleep, smoke exposure, soft bedding and sleep surfaces, and overheating. Evidence also suggests that pacifier use at sleep time and room sharing without bed sharing are associated with decreased risk of SIDS. Although the cause of SIDS is unknown, immature cardiorespiratory autonomic control and failure of arousal responsiveness from sleep are important factors. Gene polymorphisms relating to serotonin transport and autonomic nervous system development might make affected infants more vulnerable to SIDS. Campaigns for risk reduction have helped to reduce SIDS incidence by 50-90%. However, to reduce the incidence even further, greater strides must be made in reducing prenatal smoke exposure and implementing other recommended infant care practices. Continued research is needed to identify the pathophysiological basis of SIDS.
Authors:
Rachel Y Moon; Rosemary S C Horne; Fern R Hauck
Related Documents :
15342806 - Second-trimester maternal serum levels of alpha-fetoprotein and the subsequent risk of ...
17597646 - Sudden infant death syndrome: rare mutation in the serotonin system fev gene.
551926 - Sudden unexpected death in infants of narcotic-dependent mothers.
19696576 - Organ weights in cases of sudden infant death syndrome: a german study.
17874376 - Size-dependent mortality induces life-history changes mediated through population dynam...
21932586 - The effect of corrective surgery on serum igf-1, igfbp-3 levels and growth in children ...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Lancet     Volume:  370     ISSN:  1474-547X     ISO Abbreviation:  Lancet     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-11-05     Completed Date:  2007-11-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  England    
Other Details:
Languages:  eng     Pagination:  1578-87     Citation Subset:  AIM; IM    
Affiliation:
Goldberg Center for Community Pediatric Health, Children's National Medical Center and George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA. rmoon@cnmc.org
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Breast Feeding
Female
Humans
Infant
Male
Pregnancy
Prenatal Exposure Delayed Effects*
Risk Factors
Sleep
Sudden Infant Death* / epidemiology,  genetics,  prevention & control

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cost-effectiveness of drug-eluting stents in patients at high or low risk of major cardiac events in...
Next Document:  Oculoleptomeningeal amyloidosis in a patient with a TTR Val30Gly mutation in the transthyretin gene.