Document Detail

Sudden infant death syndrome: sleep apnea and respiration in subsequent siblings.
MedLine Citation:
PMID:  7402805     Owner:  NLM     Status:  MEDLINE    
Subsequent siblings of infants who died of the Sudden Infant Death Syndrome are at a four- to six-times increased risk to die of this syndrome. This study compares the respiratory development during sleep state of this epidemiologic high risk group with that of normal infants during the first six months of life. Subsequent siblings exhibited higher respiratory rates in all states at 3 months of age. Quiet sleep and indeterminate respiratory rates were elevated at 1 week of age compared to control infants. Indeterminate respiratory rates remained higher at 6 months of age. These differences were accompanied by a reduced incidence of total breathing pauses of two to five seconds and six to nine seconds duration in siblings. Study groups could not be differentiated on the basis of either breathing pauses of more than ten seconds of central apnea of six seconds or more. Obstructive and mixed apnea (6 seconds or more) were infrequently observed in these study groups. A high degree of intersubject variability characterized all data on breathing pauses.
T Hoppenbrouwers; J E Hodgman; D McGinty; R M Harper; M B Sterman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatrics     Volume:  66     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1980 Aug 
Date Detail:
Created Date:  1980-10-27     Completed Date:  1980-10-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  205-14     Citation Subset:  AIM; IM    
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MeSH Terms
Infant, Newborn
Sleep Apnea Syndromes / genetics*
Sleep Stages
Sudden Infant Death* / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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