Document Detail

Sudden infant death syndrome and maternal depression.
MedLine Citation:
PMID:  17854254     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To investigate whether there is an association between sudden infant death syndrome (SIDS) and perinatal depression. METHOD: A case-control study design was used. Cases included women registered in a British primary care database with a live birth (1987-2000) and a subsequent SIDS death. Controls were women with a live birth born in the same year as the matched SIDS death, with infant survival for the first year of life. RESULTS: One hundred sixty-nine linked mother-infant cases of SIDS were matched with 662 mother-infant controls. The authors found that SIDS was independently associated with maternal depression in the year before birth (odds ratio [OR] = 4.93, 95% CI = 1.10 to 22.05), smoking (OR = 2.50, 95% CI = 1.29 to 4.88), and male sex (OR = 1.94, 95% CI = 1.04 to 3.64). There was weak evidence of an independent association of SIDS with depression in the 6 months after birth, before the index SIDS death (OR = 1.80, 95% CI = 0.71 to 4.56). CONCLUSION: This study provides further evidence for an association between SIDS and perinatal depression, particularly antenatal depression. Health care professionals should ensure that women with perinatal depression are appropriately treated and are provided with clear advice on infant care practices that may prevent SIDS.
Louise M Howard; Graham Kirkwood; Radoslav Latinovic
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of clinical psychiatry     Volume:  68     ISSN:  1555-2101     ISO Abbreviation:  J Clin Psychiatry     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-09-14     Completed Date:  2007-09-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7801243     Medline TA:  J Clin Psychiatry     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1279-83     Citation Subset:  IM    
Health Services and Population Research Department, Institute of Psychiatry, United Kingdom.
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MeSH Terms
Antidepressive Agents / therapeutic use
Case-Control Studies
Depressive Disorder, Major / drug therapy,  epidemiology*
Infant, Newborn
Mental Disorders / classification,  epidemiology
Pregnancy Complications / drug therapy,  epidemiology*
Risk Assessment
Sudden Infant Death / epidemiology*,  prevention & control*
Reg. No./Substance:
0/Antidepressive Agents
Comment In:
J Clin Psychiatry. 2007 Aug;68(8):1277-8   [PMID:  17854253 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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