Document Detail

Sudden death in epilepsy: a study of incidence in a young cohort with epilepsy and learning difficulty.
MedLine Citation:
PMID:  7489695     Owner:  NLM     Status:  MEDLINE    
Sudden death, often seizure related, may occur in patients with epilepsy. Population-based incidence is probably on the order of 1:1,000/year. The incidence is much higher in selected groups, however. We wished to establish the incidence of sudden unexpected death (SUD) in a young cohort with severe epilepsy and learning difficulties. The study cohort included 310 pupils with epilepsy enrolled at a special residential school between April 1970 and April 1993. The follow-up period totaling 4,135 person-years included a period of residence at the school as well as time after leaving. Age and sex standardized overall mortality ratio was 15.9 [95% confidence interval (CI) 10.6-23.0], with 20 of 28 deaths considered epilepsy related. An incidence of sudden death cases of 1:295/year was noted. All 14 sudden deaths occurred when the pupils were not under the close supervision of the school and most were unwitnessed, which has implications for prevention.
L Nashef; D R Fish; S Garner; J W Sander; S D Shorvon
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Epilepsia     Volume:  36     ISSN:  0013-9580     ISO Abbreviation:  Epilepsia     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-01-04     Completed Date:  1996-01-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2983306R     Medline TA:  Epilepsia     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1187-94     Citation Subset:  IM    
Department of Clinical Neurology, Institute of Neurology, London, England.
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MeSH Terms
Age Distribution
Age Factors
Child, Preschool
Death, Sudden*
Epilepsy / mortality*
Follow-Up Studies
Seizures / mortality*

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