Document Detail

Sudden death of a horse with supraventricular tachycardia following oral administration of flecainide acetate.
MedLine Citation:
PMID:  25388866     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To describe a case of supraventricular tachycardia and sudden death in a horse following administration of flecainide acetate.
CASE SUMMARY: An 8-year-old Hanoverian warmblood gelding was treated for chronic, naturally occurring, supraventricular tachycardia with digoxin, procainamide hydrochloride, quinidine sulfate, and flecainide acetate. After oral administration of flecainide, polymorphic ventricular tachycardia (torsades de pointes) and ventricular fibrillation developed, leading to cardiovascular collapse and death.
NEW OR UNIQUE INFORMATION PROVIDED: Atrial fibrillation is the most commonly diagnosed dysrhythmia associated with poor performance in horses, while atrial tachycardia is rarely documented. Here, we describe a case of sudden death in a horse with atrial tachycardia following the oral administration of flecainide acetate, after the lack of response to other antiarrhythmic drugs. Information provided in this case report is new and will make clinicians aware of the potential complications of flecainide alone or in combination with other drugs, in horses with cardiac dysrhythmias.
Katarzyna A Dembek; Samuel D A Hurcombe; Karsten E Schober; Ramiro E Toribio
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-11-11
Journal Detail:
Title:  Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)     Volume:  -     ISSN:  1476-4431     ISO Abbreviation:  J Vet Emerg Crit Care (San Antonio)     Publication Date:  2014 Nov 
Date Detail:
Created Date:  2014-11-12     Completed Date:  -     Revised Date:  2014-11-13    
Medline Journal Info:
Nlm Unique ID:  101152804     Medline TA:  J Vet Emerg Crit Care (San Antonio)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© Veterinary Emergency and Critical Care Society 2014.
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