Document Detail


Sudden death and hepatic fatty metamorphosis. A North Carolina survey.
MedLine Citation:
PMID:  7365935     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is a generally unrecognized epidemic of sudden, nonviolent deaths among alcohol abusers, largely due to fatty liver--related sudden deaths (FLDs). Using data from the North Carolina Office of the Chief Medical Examiner, 411 cases of FLD were identified from 1972 through 1976. The 411 FLD deaths, in view of a low autopsy rate among nonviolent alcohol abuser deaths and the lack of awareness of FLD, suggest a FLD death rate of epidemic proportions. The FLD population characteristics mirror those of the underlying alcohol-abusing population. The increased incidence of low-level (1 to 50 mg/dL) blood ethanol levels among FLD as compared with "control" groups is consistent with several theories linking FLD to some form of acute or hyperacute ethanol withdrawal phenomenon.
Authors:
B Randall
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  JAMA : the journal of the American Medical Association     Volume:  243     ISSN:  0098-7484     ISO Abbreviation:  JAMA     Publication Date:  1980 May 
Date Detail:
Created Date:  1980-06-25     Completed Date:  1980-06-25     Revised Date:  2006-11-07    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1723-5     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Alcoholism / pathology
Death, Sudden / epidemiology,  pathology*
Ethanol / blood
Fatty Liver / blood,  mortality,  pathology*
Fatty Liver, Alcoholic / mortality,  pathology
Female
Humans
Liver Cirrhosis / pathology
Liver Cirrhosis, Alcoholic / mortality,  pathology
Male
Middle Aged
North Carolina
Substance Withdrawal Syndrome / pathology
Chemical
Reg. No./Substance:
64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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