Document Detail

Sudden death due to spontaneous rupture in splenic artery atypical dissection with features of vasculitis: case report and review of the literature.
MedLine Citation:
PMID:  20356693     Owner:  NLM     Status:  MEDLINE    
A case of sudden death in a 45-year-old man due to splenic artery dissection and rupture diagnosed at a medico-legal autopsy is described. The examination of the splenic artery revealed macroscopically the features of a ruptured intramural haematoma (no intimal tear, no lumen dilation) and histologically the characteristics of a lymphoplasmacytic vasculitis of the vasa vasorum associated with fibrinoid degeneration. The patient died at home after having been discharged from hospital where he had presented for modest abdominal pain with no evidence of the true nature of the disease found using echography. The Authors discuss the literature relative to splenic artery dissection (13 cases of which only one diagnosed in vivo), the present case being the only one due to vasculitis of the vasa vasorum and the forensic implications (autopsy was ordered to examine the causes of death, to verify whether diagnosis could have been reached during hospitalization with consequences on the outcome and if a hypothesis of malpractice could be prospected).
Lorenzo Desinan; Cathryn Anne Scott; Iginio Piai; Gionata Maria Mazzolo
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2010-03-30
Journal Detail:
Title:  Forensic science international     Volume:  200     ISSN:  1872-6283     ISO Abbreviation:  Forensic Sci. Int.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-08     Completed Date:  2010-10-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902034     Medline TA:  Forensic Sci Int     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  e1-5     Citation Subset:  IM    
Copyright Information:
(c) 2010 Elsevier Ireland Ltd. All rights reserved.
Institute of Legal Medicine, University of Udine, Italy.
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MeSH Terms
Aneurysm, Dissecting / pathology*
Death, Sudden / etiology*
Forensic Pathology
Hematoma / pathology
Hemorrhage / pathology
Middle Aged
Rupture, Spontaneous
Splenic Artery / pathology
Splenic Rupture / pathology*
Vasa Vasorum / pathology
Vasculitis / pathology

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