| Sudden death due to giant cell coronary arteritis. | |
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MedLine Citation:
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PMID: 16642350 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An 89-year-old woman was found dead lying in her bed. Autopsy demonstrated a pronounced thickening of all coronary arteries except for the first 2-4 cm. Death was due to a recent myocardial infarction. Microscopically, the coronary arteries showed a substantial concentric thickening of all three layers with 90% narrowing. There was a dense transmural inflammatory infiltration with lymphocytes, macrophages, and numerous multinucleated giant cells. The CD68 positive giant cells were mostly located at the media-intima border in the vicinity of fragmented fibers of the lamina elastica interna. The aorta and its major branches including the carotid arteries, however, were free of inflammation and thickening. The findings were characteristic for giant cell arteritis, the equivalent of temporal Horton arteritis, but isolated involvement of the coronary arteries is exceptional. |
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Authors:
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B Karger; G Fechner |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2006-04-27 |
Journal Detail:
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Title: International journal of legal medicine Volume: 120 ISSN: 0937-9827 ISO Abbreviation: Int. J. Legal Med. Publication Date: 2006 Nov |
Date Detail:
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Created Date: 2006-10-24 Completed Date: 2007-06-04 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9101456 Medline TA: Int J Legal Med Country: Germany |
Other Details:
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Languages: eng Pagination: 377-9 Citation Subset: IM |
Affiliation:
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Institute of Legal Medicine, University of Münster, Röntgenstrasse 23, 48149 Münster, Germany. karger@uni-muenster.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged, 80 and over Aorta / pathology Coronary Vessels / pathology Death, Sudden / etiology* Female Forensic Pathology Giant Cell Arteritis / diagnosis* Giant Cells / pathology Humans Lymphocytes / pathology Macrophages / pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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