Document Detail


Sudden unexpected death in infancy associated with an epithelial-type hepatoblastoma in a 6-month-old infant.
MedLine Citation:
PMID:  20170276     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sudden unexpected death in infancy and childhood attributable to undiagnosed neoplasia is rare. Malignant neoplasms are very uncommon in infancy, with an age-standardized incidence rate of 118.3 per million. Primary malignant liver tumors are rare, with hepatoblastoma accounting for up to two thirds of cases. Although hepatoblastoma is the most common malignant neoplasm of the liver in childhood, it only accounts for 3.1% of childhood cancers for infants less than 12 months of age. We describe the first case of sudden death in an apparently healthy 6-month-old infant whose autopsy revealed an epithelial type hepatoblastoma with mixed fetal and embryonal patterns.
Authors:
Jeremy Pryce; Liina Kiho; Irene Scheimberg
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  13     ISSN:  1093-5266     ISO Abbreviation:  Pediatr. Dev. Pathol.     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-10-07     Completed Date:  2010-11-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  338-40     Citation Subset:  IM    
Affiliation:
Department of Cellular Pathology, The Royal London Hospital, Barts and The London NHS Trust, Pathology and Pharmacy Building, 80 Newark Street, London E1 2ES, UK.
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MeSH Terms
Descriptor/Qualifier:
Failure to Thrive
Female
Hepatoblastoma / complications,  pathology*
Humans
Infant
Liver Neoplasms / complications,  pathology*
Sudden Infant Death / etiology,  pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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