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Sudden Cardiac Arrest: ECG Repolarization After Resuscitation.
MedLine Citation:
PMID:  20731741     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Sudden Cardiac Arrest and ECG Repolarization. Introduction: Early repolarization (ERep) abnormalities on electrocardiogram (ECG) are common immediately following cardiac arrest. We characterized and correlated electrocardiographic repolarization abnormalities immediately after cardiac arrest with acute coronary angiography. Methods and Results: We studied 225 consecutive patients presenting with out-of-hospital cardiac arrest. All these patients had successful cardiopulmonary resuscitation and acute coronary angiography. The first ECG recorded after successful resuscitation was analyzed by two independent cardiologists. Patients were categorized according to their repolarization pattern. Pattern 1: No ST segment elevation or ERep. Pattern 2: ST segment elevation without ERep. Pattern 3: ST segment elevation and ERep. Pattern 4: ERep only. Patterns 1, 2, 3, and 4 were found in 112 (50%), 74 (33%), 19 (8%), and 20 (9%) patients, respectively. Cardiac arrest was due to acute myocardial ischemia in 45%, 82%, 39%, and 15% of patients in groups 1, 2, 3 and 4, respectively (P < 0.0001). Sensitivity and specificity of pattern 2 was 50% and 88%, respectively, for acute coronary lesion, whereas isolated ERep pattern occurred in 9% of cases and was associated with a nonischemic event (80%). Among 65 patients (29%) who survived, 7% of patients with pattern 1, 13% with pattern 2, 60% with pattern 3, and 88% with pattern 4 exhibited ERep on ECG during the follow-up. Conclusion: In the context of cardiac resuscitation, an ECG with ST elevation favors acute myocardial infarction, whereas the presence of ERep is a marker of a nonischemic event and future ERep syndrome. (J Cardiovasc Electrophysiol, Vol. 22, pp. 131-136, February 2011).
Authors:
Nicolas Lellouche; Frederic Sacher; Pierre Jorrot; Alain Cariou; Christian Spaulding; Amandine Aurore; Xavier Combes; Jerome Fichet; Emmanuel Teiger; Pierre Jais; Jean-Luc Dubois-Randé; Michel Haissaguerre
Publication Detail:
Type:  Journal Article     Date:  2010-08-19
Journal Detail:
Title:  Journal of cardiovascular electrophysiology     Volume:  22     ISSN:  1540-8167     ISO Abbreviation:  J. Cardiovasc. Electrophysiol.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9010756     Medline TA:  J Cardiovasc Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  131-6     Citation Subset:  IM    
Copyright Information:
© 2010 Wiley Periodicals, Inc.
Affiliation:
Hôpital Henri Mondor, Assistance Publique Hôpitaux de Paris et INSERM U 841, Creteil, France Hopital Cardiologique du Haut-Leveque, CHU de Bordeaux/Université Bordeaux II, Pessac Cedex, France Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Saint-Jacques, Paris, France.
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