Document Detail

Sucrose analgesia for minor procedures in newborn infants.
MedLine Citation:
PMID:  11485149     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the role of intraoral sucrose and other sweet-tasting solutions for the management of pain associated with minor procedures in newborns. DATA SOURCES: A search of MEDLINE articles from 1966 to August 1999 and an extensive review of journals was conducted. MeSH headings included analgesia, sucrose, and neonate. DATA SYNTHESIS: Newborn infants regularly undergo minor invasive procedures for which analgesics are not routinely used. Intraoral sucrose and other sweet-tasting solutions appear to diminish surrogate biomarkers of pain response as evidenced by a reduction in crying time, smaller increases in heart rate, and lower pain scale ratings. CONCLUSIONS: These studies appear to suggest that sucrose solution 0.5 g provides effective analgesia with no reported adverse effects.
L D Masters-Harte; S M Abdel-Rahman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Annals of pharmacotherapy     Volume:  35     ISSN:  1060-0280     ISO Abbreviation:  Ann Pharmacother     Publication Date:    2001 Jul-Aug
Date Detail:
Created Date:  2001-08-03     Completed Date:  2001-12-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9203131     Medline TA:  Ann Pharmacother     Country:  United States    
Other Details:
Languages:  eng     Pagination:  947-52     Citation Subset:  IM    
Children's Mercy Hospital, Kansas City, MO 64108-4698, USA.
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MeSH Terms
Heart Rate
Infant, Newborn
Pain / prevention & control*
Pain Measurement
Randomized Controlled Trials as Topic
Surgical Procedures, Minor
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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