Document Detail


Sucralose sweetener in vivo effects on blood constituents radiolabeling, red blood cell morphology and radiopharmaceutical biodistribution in rats.
MedLine Citation:
PMID:  20801049     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Effects of sucralose sweetener on blood constituents labelled with technetium-99m ((99m)Tc) on red blood cell (RBC) morphology, sodium pertechnetate (Na(99m)TcO(4)) and diethylenetriaminepentaacetic acid labeled with (99m)Tc ((99m)Tc-DTPA) biodistribution in rats were evaluated. Radiolabeling on blood constituents from Wistar rats was undertaken for determining the activity percentage (%ATI) on blood constituents. RBC morphology was also evaluated. Na(99m)TcO(4) and (99m)Tc-DTPA biodistribution was used to determine %ATI/g in organs. There was no alteration on RBC blood constituents and morphology %ATI. Sucralose sweetener was capable of altering %ATI/g of the radiopharmaceuticals in different organs. These findings are associated to the sucralose sweetener in specific organs.
Authors:
G S Rocha; M O Pereira; M O Benarroz; J N G Frydman; V C Rocha; M J Pereira; A S Fonseca; A C Medeiros; M Bernardo-Filho
Related Documents :
1402469 - Thalassemic red cells determined by different technology of blood cell analysers.
1484089 - Investigation of red blood cell fractionation by gravitational field-flow fractionation.
7631349 - Circulation of red blood cells having high levels of 2,3-bisphosphoglycerate protects r...
15373519 - Dna from urine sediment or buccal cells can be used for blood group molecular genotyping.
20415489 - Paper diagnostic for instantaneous blood typing.
3779059 - Execution of "arc" experiment on space shuttle "discovery" sts 51-c: some results on ag...
7274559 - The belgian plasmapheresis programme.
1402469 - Thalassemic red cells determined by different technology of blood cell analysers.
21227579 - Critical air/water blow-down in safety valves at low qualities.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-08-17
Journal Detail:
Title:  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine     Volume:  69     ISSN:  1872-9800     ISO Abbreviation:  Appl Radiat Isot     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-10-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9306253     Medline TA:  Appl Radiat Isot     Country:  England    
Other Details:
Languages:  eng     Pagination:  46-51     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Universidade do Estado do Rio de Janeiro, Instituto de Biologia Roberto Alcantara Gomes, Departamento de Biofísica e Biometria, Avenida 28 de Setembro, 87, Vila Isabel, 20551030 Rio de Janeiro, Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Novel imidazoline compounds as partial or full agonists of D2-like dopamine receptors inspired by I2...
Next Document:  Chest-tube digital assessment after pulmonary resection: the crucial role of time-trend analysis and...