Document Detail

Sucralfate suspension as a treatment of recurrent aphthous stomatitis.
MedLine Citation:
PMID:  8077892     Owner:  NLM     Status:  MEDLINE    
DESIGN: A prospective randomized, double-blind, placebo-controlled, cross-over clinical trial. SETTING: A university hospital. SUBJECTS: Twenty-one patients with symptomatic recurrent aphthous stomatitis (RAS), unresponsive to conventional treatment were enrolled. They were divided into three groups. INTERVENTION: In a cross-over trial, the patients received an oral suspension of sucralfate, an antacid solution or a placebo for 2 years. RESULTS: After 2 years of follow-up, sucralfate was found to be superior to both placebo and antacid (P < 0.001) with regard to duration of pain, reduction of the healing period, response time to first treatment and duration of remission. CONCLUSION: Sucralfate suspension should be added to the armament of treatment modalities of RAS.
J Rattan; M Schneider; N Arber; M Gorsky; D Dayan
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of internal medicine     Volume:  236     ISSN:  0954-6820     ISO Abbreviation:  J. Intern. Med.     Publication Date:  1994 Sep 
Date Detail:
Created Date:  1994-09-30     Completed Date:  1994-09-30     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  8904841     Medline TA:  J Intern Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  341-3     Citation Subset:  IM    
Department of Gastroenterology, Tel Aviv Medical Centre, Sackler School of Medicine, Israel.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Administration, Buccal
Antacids / therapeutic use
Child, Preschool
Double-Blind Method
Middle Aged
Prospective Studies
Stomatitis, Aphthous / drug therapy*
Sucralfate / administration & dosage,  therapeutic use*
Treatment Outcome
Reg. No./Substance:
0/Antacids; 0/Suspensions; 54182-58-0/Sucralfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Cardiovascular risk factors in a Melanesian population apparently free from stroke and ischaemic hea...
Next Document:  Giant-cell arteritis of the female genital tract.