| Sucralfate suspension as a treatment of recurrent aphthous stomatitis. | |
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MedLine Citation:
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PMID: 8077892 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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DESIGN: A prospective randomized, double-blind, placebo-controlled, cross-over clinical trial. SETTING: A university hospital. SUBJECTS: Twenty-one patients with symptomatic recurrent aphthous stomatitis (RAS), unresponsive to conventional treatment were enrolled. They were divided into three groups. INTERVENTION: In a cross-over trial, the patients received an oral suspension of sucralfate, an antacid solution or a placebo for 2 years. RESULTS: After 2 years of follow-up, sucralfate was found to be superior to both placebo and antacid (P < 0.001) with regard to duration of pain, reduction of the healing period, response time to first treatment and duration of remission. CONCLUSION: Sucralfate suspension should be added to the armament of treatment modalities of RAS. |
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Authors:
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J Rattan; M Schneider; N Arber; M Gorsky; D Dayan |
Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Journal of internal medicine Volume: 236 ISSN: 0954-6820 ISO Abbreviation: J. Intern. Med. Publication Date: 1994 Sep |
Date Detail:
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Created Date: 1994-09-30 Completed Date: 1994-09-30 Revised Date: 2010-03-24 |
Medline Journal Info:
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Nlm Unique ID: 8904841 Medline TA: J Intern Med Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 341-3 Citation Subset: IM |
Affiliation:
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Department of Gastroenterology, Tel Aviv Medical Centre, Sackler School of Medicine, Israel. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Buccal Adolescent Adult Aged Antacids / therapeutic use Child Child, Preschool Double-Blind Method Female Humans Male Middle Aged Prospective Studies Recurrence Stomatitis, Aphthous / drug therapy* Sucralfate / administration & dosage, therapeutic use* Suspensions Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antacids; 0/Suspensions; 54182-58-0/Sucralfate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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