| Successful use of recombinant factor VIIa in a preterm infant with life-threatening haematuria. | |
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MedLine Citation:
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PMID: 19730247 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report the case of a preterm male infant with a gestational age of 28 + 1 weeks and birth weight of 715 g who presented with life-threatening haematuria on day 28 of life. The haematuria was unresponsive to administration of platelet concentrates and fresh frozen plasma, but then successfully treated with recombinant factor VIIa. The resulting obstructive uropathy was managed by continuous bladder irrigation through suprapubic and urethral catheters. No other adverse affects were noted, and the boy was discharged from the hospital on day 108 of life. |
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Authors:
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Kirstin Faust; Birthe Tröger; Fritz Kahl; Marius Schumacher; Wolfgang Göpel; Christoph Härtel |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis Volume: 20 ISSN: 1473-5733 ISO Abbreviation: Blood Coagul. Fibrinolysis Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2010-06-03 Completed Date: 2010-09-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9102551 Medline TA: Blood Coagul Fibrinolysis Country: England |
Other Details:
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Languages: eng Pagination: 601-4 Citation Subset: IM |
Affiliation:
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Department of Children's and Adolescent's Medicine, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany. faust@paedia.ukl.mu-luebeck.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Critical Illness Factor VIIa / therapeutic use* Hematuria / complications, drug therapy* Humans Infant, Newborn Infant, Premature Male Recombinant Proteins / therapeutic use Treatment Outcome Urethral Obstruction / etiology, therapy |
| Chemical | |
Reg. No./Substance:
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0/Recombinant Proteins; 0/recombinant FVIIa; EC 3.4.21.21/Factor VIIa |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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