Document Detail


Successful use of recombinant factor VIIa in a preterm infant with life-threatening haematuria.
MedLine Citation:
PMID:  19730247     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the case of a preterm male infant with a gestational age of 28 + 1 weeks and birth weight of 715 g who presented with life-threatening haematuria on day 28 of life. The haematuria was unresponsive to administration of platelet concentrates and fresh frozen plasma, but then successfully treated with recombinant factor VIIa. The resulting obstructive uropathy was managed by continuous bladder irrigation through suprapubic and urethral catheters. No other adverse affects were noted, and the boy was discharged from the hospital on day 108 of life.
Authors:
Kirstin Faust; Birthe Tröger; Fritz Kahl; Marius Schumacher; Wolfgang Göpel; Christoph Härtel
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis     Volume:  20     ISSN:  1473-5733     ISO Abbreviation:  Blood Coagul. Fibrinolysis     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2010-06-03     Completed Date:  2010-09-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102551     Medline TA:  Blood Coagul Fibrinolysis     Country:  England    
Other Details:
Languages:  eng     Pagination:  601-4     Citation Subset:  IM    
Affiliation:
Department of Children's and Adolescent's Medicine, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany. faust@paedia.ukl.mu-luebeck.de
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MeSH Terms
Descriptor/Qualifier:
Critical Illness
Factor VIIa / therapeutic use*
Hematuria / complications,  drug therapy*
Humans
Infant, Newborn
Infant, Premature
Male
Recombinant Proteins / therapeutic use
Treatment Outcome
Urethral Obstruction / etiology,  therapy
Chemical
Reg. No./Substance:
0/Recombinant Proteins; 0/recombinant FVIIa; EC 3.4.21.21/Factor VIIa

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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