Document Detail

Successful use of recombinant factor VIIa in a preterm infant with life-threatening haematuria.
MedLine Citation:
PMID:  19730247     Owner:  NLM     Status:  MEDLINE    
We report the case of a preterm male infant with a gestational age of 28 + 1 weeks and birth weight of 715 g who presented with life-threatening haematuria on day 28 of life. The haematuria was unresponsive to administration of platelet concentrates and fresh frozen plasma, but then successfully treated with recombinant factor VIIa. The resulting obstructive uropathy was managed by continuous bladder irrigation through suprapubic and urethral catheters. No other adverse affects were noted, and the boy was discharged from the hospital on day 108 of life.
Kirstin Faust; Birthe Tröger; Fritz Kahl; Marius Schumacher; Wolfgang Göpel; Christoph Härtel
Related Documents :
25365287 - Predicting transition to the supine sleep position in preterm infants.
1003267 - Epignathus, double pituitary and agenesis of corpus callosum.
25280497 - Recognition and reporting of aki in very low birth weight infants.
9650227 - Ethical dilemmas in the delivery room.
8784027 - Massive right ventricular fibroma treated with partial resection and a cavopulmonary sh...
16198967 - A study of homicidal deaths in medico-legal autopsies at ummc, kuala lumpur.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis     Volume:  20     ISSN:  1473-5733     ISO Abbreviation:  Blood Coagul. Fibrinolysis     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2010-06-03     Completed Date:  2010-09-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102551     Medline TA:  Blood Coagul Fibrinolysis     Country:  England    
Other Details:
Languages:  eng     Pagination:  601-4     Citation Subset:  IM    
Department of Children's and Adolescent's Medicine, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Critical Illness
Factor VIIa / therapeutic use*
Hematuria / complications,  drug therapy*
Infant, Newborn
Infant, Premature
Recombinant Proteins / therapeutic use
Treatment Outcome
Urethral Obstruction / etiology,  therapy
Reg. No./Substance:
0/Recombinant Proteins; 0/recombinant FVIIa; EC VIIa

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Thrombin generation assay as a possible tool for assessment of reduced activity of clotting factors ...
Next Document:  Prevalence of factor V Leiden and prothrombin G20210A mutation in a large French population selected...