Document Detail

Successful use of maternal blood in the management of severe hemolytic disease of the fetus and newborn due to anti-Kp(b).
MedLine Citation:
PMID:  20951648     Owner:  NLM     Status:  In-Process    
BACKGROUND: The incidence of hemolytic disease of the fetus and newborn (HDFN) has decreased since the introduction of Rh immunoglobulin prophylaxis in Rh(D)-negative pregnant women. Thus, the relative incidence of rare alloantibody-related HDFN has increased. The lack of available maternally matched red blood cells for transfusion in these cases may create management difficulties.
CASE: We report a case of anti-Kp(b) HDFN. Severe fetal anemia required intrauterine transfusion. Difficulty in obtaining Kp(b)-negative blood necessitated using the mother's donated RBCs.
CONCLUSION: Severe HDFN with rare antibodies can be managed successfully using maternal blood.
Michelle J Bleile; Asha Rijhsinghani; Denis M Dwyre; Thomas J Raife
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Publication Detail:
Type:  Journal Article     Date:  2010-10-15
Journal Detail:
Title:  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis     Volume:  43     ISSN:  1473-0502     ISO Abbreviation:  Transfus. Apher. Sci.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101095653     Medline TA:  Transfus Apher Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  281-3     Citation Subset:  T    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Department of Pathology, Roy J and Lucille A Carver College of Medicine, and University of Iowa, Iowa City, IA 52242, United States.
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