Document Detail


Successful use of all-trans retinoic acid in acute promyelocytic leukaemia presenting during the second trimester of pregnancy.
MedLine Citation:
PMID:  8043456     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The development of acute leukaemia in pregnancy is a rare event, with an estimated incidence of 0.9-1.2 cases per 100,000 per year and with the majority of cases occurring in the second and third trimesters. We report a case of acute promyelocytic leukaemia (APL) developing during the second trimester of pregnancy which was successfully treated with all-trans retinoic acid (ATRA) resulting in a complete morphological remission.
Authors:
P Harrison; P Chipping; G A Fothergill
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  British journal of haematology     Volume:  86     ISSN:  0007-1048     ISO Abbreviation:  Br. J. Haematol.     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-09-01     Completed Date:  1994-09-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372544     Medline TA:  Br J Haematol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  681-2     Citation Subset:  IM    
Affiliation:
Department of Haematology, North Staffordshire Hospital, Stoke-on-Trent.
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Humans
Leukemia, Promyelocytic, Acute / drug therapy*
Pregnancy
Pregnancy Complications, Neoplastic / drug therapy*
Pregnancy Trimester, Second
Tretinoin / therapeutic use*
Chemical
Reg. No./Substance:
302-79-4/Tretinoin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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