| Successful treatment with intraarticular infliximab for resistant knee monarthritis in a patient with spondylarthropathy: a role for scintigraphy with 99mTc-infliximab. | |
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MedLine Citation:
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PMID: 15818709 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Positive experiences with intraarticular infliximab have been reported in patients with rheumatoid arthritis, ankylosing spondylitis, and Behcet's disease. We used intraarticular infliximab to treat resistant knee monarthritis in a patient with spondylarthropathy. Clinical and laboratory improvement was associated with improvement in scintigraphic findings. This approach is less expensive than intravenous administration of infliximab. We suggest that selection of candidates for this innovative therapy should be guided by anti-tumor necrosis factor alpha scintigraphy. |
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Authors:
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Fabrizio Conti; Roberta Priori; Maria Sole Chimenti; Giulio Coari; Alessio Annovazzi; Guido Valesini; Alberto Signore |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Arthritis and rheumatism Volume: 52 ISSN: 0004-3591 ISO Abbreviation: Arthritis Rheum. Publication Date: 2005 Apr |
Date Detail:
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Created Date: 2005-04-13 Completed Date: 2005-05-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370605 Medline TA: Arthritis Rheum Country: United States |
Other Details:
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Languages: eng Pagination: 1224-6 Citation Subset: AIM; IM |
Affiliation:
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Università degli Studi di Roma La Sapienza, Rome, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antibodies, Monoclonal / administration & dosage, therapeutic use* Antirheumatic Agents / administration & dosage, therapeutic use* Arthritis, Rheumatoid / complications, diagnosis, drug therapy* Humans Injections, Intra-Articular Knee Joint / drug effects, metabolism Male Radionuclide Imaging Spondylitis, Ankylosing / complications, diagnosis, drug therapy* Technetium / diagnostic use Treatment Outcome Tumor Necrosis Factor-alpha / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/Antirheumatic Agents; 0/Tumor Necrosis Factor-alpha; 0/infliximab; 7440-26-8/Technetium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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