| Successful treatment with ICSI of infertility caused by azoospermia associated with adrenal rests in the testes: case report. | |
| | |
MedLine Citation:
|
PMID: 11157817 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Congenital adrenal hyperplasia (CAH) is a well-recognized, but uncommon, cause of azoospermia and infertility in men. Commonly this is due to undertreatment of excessive adrenal androgen secretion which suppresses gonadotrophin stimulation of the testes. A less common complication of CAH is development of adrenal tissue within the testes; this is important to recognize because it may be confused with malignancy leading to unnecessary surgery. In this case report, a man is described with simple virilizing CAH due to 21-hydroxylase deficiency who presented with azoospermia and was found to have adrenal rests. Investigations concluded that there was adequate adrenal suppression with glucocorticoids and that azoospermia was due to obstruction by adrenal rest tissue, strategically situated at the hilum of the testes. Spermatozoa were able to be retrieved by testicular aspiration from the man and these were used to successfully establish a pregnancy using intracytoplasmic sperm injection of his wife's oocytes. |
| | |
Authors:
|
H Murphy; C George; D de Kretser ; S Judd |
Related Documents
:
|
7675397 - Diagnosis and surgical treatment of primary aldosteronism in pregnancy: a case report. 8162167 - Brain lys-aminopeptidase activity. changes during cycle and pregnancy. 1848507 - Effect of adrenocorticotropin administration on the biosynthesis of corticosteroid-bind... 3400697 - Pituitary gland growth during normal pregnancy: an in vivo study using magnetic resonan... 8437797 - Fetal hemivertebrae: associated anomalies, significance, and outcome. 3067167 - The use of doppler waveform analysis in the evaluation of the high-risk fetus. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Human reproduction (Oxford, England) Volume: 16 ISSN: 0268-1161 ISO Abbreviation: Hum. Reprod. Publication Date: 2001 Feb |
Date Detail:
|
Created Date: 2001-02-22 Completed Date: 2001-05-10 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8701199 Medline TA: Hum Reprod Country: England |
Other Details:
|
Languages: eng Pagination: 263-7 Citation Subset: IM |
Affiliation:
|
Departments of Medicine and Reproductive Medicine, Flinders Medical Centre, Bedford Park, South Australia, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adrenal Hyperplasia, Congenital
/
complications*,
drug therapy Adrenal Rest Tumor / complications*, diagnosis Adult Female Glucocorticoids / therapeutic use Humans Infant, Newborn Male Oligospermia / etiology*, therapy* Prednisolone / therapeutic use Pregnancy Pregnancy Outcome Sperm Injections, Intracytoplasmic* Testicular Neoplasms / complications*, diagnosis |
| Chemical | |
Reg. No./Substance:
|
0/Glucocorticoids; 50-24-8/Prednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cumulative conception and live birth rates in natural (unstimulated) IVF cycles.
Next Document: Successful pregnancy by transmyometrial and transtubal embryo transfer after IVF in a patient with c...