Document Detail

Successful treatment of widespread eczema and sleep disruption in a 7-month-old infant with methylprednisolone aceponate 0.1%.
MedLine Citation:
PMID:  23067434     Owner:  NLM     Status:  In-Data-Review    
A 7-month-old infant, with no known food allergy or intolerance, presenting with eczema lesions affecting many parts of his body, was diagnosed with infantile eczema. A skin barrier defect, due to filaggrin deficiency, was suspected. Prior treatment with emollients was not effective and produced discomfort. After twice-daily application of methylprednisolone aceponate (MPA) 0.1% (Advantan(®) ), in addition to temporary withdrawal of emollients, for 10 days. At the follow-up examination, improvements in all eczema lesions, scratching behavior and sleep quality were observed, and eczema was considered almost clear and under control. Advantan was prescribed to control new flares of eczema, and heavy emollients were recommended to treat residual dryness and damage from original lesions. No side effects of Advantan were reported. In an infant with newly diagnosed eczema, Advantan was safe and effective in alleviating lesions and scratching severity and restoring sleep.
A Torrelo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the European Academy of Dermatology and Venereology : JEADV     Volume:  26 Suppl 6     ISSN:  1468-3083     ISO Abbreviation:  J Eur Acad Dermatol Venereol     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9216037     Medline TA:  J Eur Acad Dermatol Venereol     Country:  England    
Other Details:
Languages:  eng     Pagination:  16-7     Citation Subset:  IM    
Copyright Information:
© 2012 The Author. Journal of the European Academy of Dermatology and Venereology © 2012 European Academy of Dermatology and Venereology.
Department of Pediatric Dermatology, Hospital del Niño Jesús, Madrid, Spain.
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