Document Detail


Successful treatment using cyclosporine in a patient with rhupus complicated by aplastic anemia: a case report and review of the literature.
MedLine Citation:
PMID:  21813067     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Systemic lupus erythematosus (SLE) comorbid with rheumatoid arthritis (RA) is known as 'Rhupus syndrome' and is estimated to be present in between 0.01 and 2% of SLE and RA patients. The occurrence of aplastic anaemia in a patient with rhupus is very rare and a treatment for this condition has not been reported. A 52-year-old woman presented complaining of nausea and dizziness during the preceding month. She had been treated for rheumatoid arthritis for 16 years. At the time of presentation, she had a malar rash, multiple arthritis, pancytopenia, pleural effusion, proteinuria, and positive anti-nuclear and anti-dsDNA antibodies. A kidney biopsy revealed ISN/RPS class IV-G (A) lupus nephritis. Bone marrow aspiration and biopsy showed aplastic anaemia with no evidence of viral infection. The patient was successfully treated using cyclosporine and prednisolone and she remained symptom-free at the one-and-a-half-year follow-up. To our knowledge, this is the first report of a successful treatment using cyclosporine in a patient with rhupus complicated by aplastic anaemia.
Authors:
Seong-Rye Seo; Sung-Ji Lee; Dong-Jin Park; Tae-Jong Kim; Yong-Wook Park; Shin-Seok Lee
Related Documents :
10785837 - Imaging of nonmotor symptoms in parkinson syndromes.
19076287 - Advanced oxidative protein products are independently associated with endothelial funct...
22566977 - Predictors of the intracerebral hemorrhage volume in hypertensive patients.
12821507 - Dysfunction of the basal ganglia, but not the cerebellum, impairs kinaesthesia.
1675547 - Organic vs functional obstruction of the fallopian tubes: differentiation with prostagl...
24996047 - Development and validation of a polycystic liver disease-complaint-specific-assessment ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-14
Journal Detail:
Title:  Clinical and experimental rheumatology     Volume:  -     ISSN:  0392-856X     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-8-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8308521     Medline TA:  Clin Exp Rheumatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Rheumatology, Chonnam National University Medical School, Gwangju, South Korea. snoopy7796@hanmail.net.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Association of anti-CCP positivity and carriage of TNFRII susceptibility variant with anti-TNF? resp...
Next Document:  Optimising bisphosphonate treatment outcomes in postmenopausal osteoporosis: review and Italian expe...