Document Detail


Successful treatment of a squamous cell carcinoma in a white rhinoceros, Ceratotherium simum.
MedLine Citation:
PMID:  17991166     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A captive 33-year-old male white rhinoceros with seasonal dermatitis was diagnosed with a malignant squamous cell carcinoma on the right flank. Staphylococcus aureus was cultured from the skin lesions. No fungal or yeast was isolated. The dermatitis was treated with a combination of oral antibiotics (trimethoprim-sulphadiazine) and topically with weekly chlorhexidine washes and a mixture of a zinc oxide, balsam peru and bismuth oxide cream. Under azaperone and butorphanol anaesthesia, the skin tumour was surgically removed. The tumour was excised with wide margins and allowed to heal by secondary intention as primary wound closure was not possible. A post-mortem performed 2 years later for an unrelated condition revealed no metastases or recurrence of the skin tumour. It was presumed that chronic irritation or trauma may have contributed to the development of the skin tumour. This is the first detailed report of the successful treatment of a squamous cell carcinoma not associated with the horn in a rhinoceros.
Authors:
Gidona Goodman; Susan Rhind; Anna Meredith
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Veterinary dermatology     Volume:  18     ISSN:  0959-4493     ISO Abbreviation:  Vet. Dermatol.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-09     Completed Date:  2008-01-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9426187     Medline TA:  Vet Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  460-3     Citation Subset:  IM    
Affiliation:
Department of Veterinary Clinical Studies, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Roslin, Midlothian EH25 9RG, UK. ggoodman@vet.ed.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Animals
Anti-Bacterial Agents / administration & dosage,  therapeutic use
Carcinoma, Squamous Cell / complications,  diagnosis,  surgery,  veterinary*
Diagnosis, Differential
Male
Perissodactyla*
Skin Neoplasms / complications,  diagnosis,  surgery,  veterinary*
Staphylococcal Skin Infections / complications,  diagnosis,  drug therapy,  veterinary*
Trimethoprim-Sulfamethoxazole Combination / administration & dosage,  therapeutic use
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 8064-90-2/Trimethoprim-Sulfamethoxazole Combination

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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