Document Detail

Successful treatment of a severe second trimester fetomaternal hemorrhage by repeated fetal intravascular transfusions.
MedLine Citation:
PMID:  19145084     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: It was the aim of this study to report a case of fetomaternal hemorrhage (FMH) that was successfully treated with fetal intravascular transfusions in which the middle cerebral artery peak systolic velocity (MCA-PSV) detected fetal anemia. METHODS: A massive FMH occurred twice in a healthy 33-year-old pregnant woman at 26 and 29 weeks of gestation with no evident cause. Four repeated intravascular transfusions were performed. The MCA-PSV increased in the presence of anemia and decreased following correction of fetal hematocrit. RESULTS: A healthy neonate was delivered at 33 weeks of gestation. CONCLUSION: MCA-PSV detected fetal anemia both before the first transfusion and following the next intravascular transfusions. In our case, the change in fetal blood viscosity following transfusion with adult blood did not affect the MCA-PSV value for detection of fetal anemia.
Carmela Votino; Véronique Mirlesse; Luc Gourand; Françoise Parnet-Mathieu; Bettina Bessières; Fernand Daffos
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-01-15
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  24     ISSN:  1421-9964     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:  2008  
Date Detail:
Created Date:  2009-01-30     Completed Date:  2009-04-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  503-5     Citation Subset:  IM    
Copyright Information:
Copyright 2009 S. Karger AG, Basel.
Fetal Medicine Unit, Institut de Puériculture, Paris, France.
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MeSH Terms
Anemia / therapy
Blood Flow Velocity
Blood Transfusion, Intrauterine*
Fetomaternal Transfusion / therapy*
Infant, Newborn
Middle Cerebral Artery / physiology
Pregnancy Trimester, Second
Severity of Illness Index

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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