Document Detail

Successful treatment of recurrent, intractable hyperemesis gravidarum with methylprednisolone. A case report.
MedLine Citation:
PMID:  12746996     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Severe and persistent hyperemesis gravidarum is a disabling condition. Women may request termination of pregnancy because of the intolerable symptoms and stress. CASE: A woman requested termination of pregnancy because of severe hyperemesis gravidarum. Her first three pregnancies were also complicated by severe and persistent vomiting. The vomiting was successfully treated with a short course of methylprednisolone. CONCLUSION: Methylprednisolone is an effective treatment for severe hyperemesis gravidarum and should be considered for women whose vomiting is persistent and refractory to conventional therapy.
Louis Y Chan; Man Ho Lam; Tze Kin Lau; Robert K H Chin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  48     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-05-15     Completed Date:  2003-08-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  293-5     Citation Subset:  IM    
Departments of Obstetrics and Gynaecology, Princes of Wales Hospital, Chinese University of Hong Kong, and Princess Margaret Hospital, Shatin, Hong Kong.
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MeSH Terms
Dose-Response Relationship, Drug
Drug Administration Schedule
Follow-Up Studies
Hyperemesis Gravidarum / diagnosis*,  drug therapy*
Methylprednisolone / administration & dosage*
Pregnancy Complications / diagnosis,  drug therapy*
Pregnancy Outcome*
Pregnancy Trimester, First
Severity of Illness Index
Reg. No./Substance:

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