Document Detail

Successful treatment of a pregnant woman with Philadelphia chromosome-positive acute lymphoblastic leukemia.
MedLine Citation:
PMID:  23359302     Owner:  NLM     Status:  Publisher    
The management of acute leukemia during pregnancy is challenging. Delays in treatment for acute leukemia can adversely affect maternal prognosis, but chemotherapy during pregnancy may induce severe adverse effects on the fetus. Here, we report a case of a pregnant woman with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph(+)ALL) who underwent remission induction therapy and successfully delivered a live infant after chemotherapy. The case is a 36-year-old woman diagnosed with Ph(+)ALL in the 27th week of pregnancy. She underwent remission induction therapy including daunorubicin, vincristine, cyclophosphamide, and prednisolone. Imatinib was not used in the induction therapy. She delivered the infant after one course of chemotherapy. The infant and the patient are both alive now, without any major complications.
Yuki Nakajima; Hideyuki Kuwabara; Yukako Hattori; Rika Ohshima; Rika Sakai; Masakazu Kitagawa; Naoto Tomita; Yoshiaki Ishigatsubo; Shin Fujisawa
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-29
Journal Detail:
Title:  International journal of hematology     Volume:  -     ISSN:  1865-3774     ISO Abbreviation:  Int. J. Hematol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111627     Medline TA:  Int J Hematol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Hematology, Yokohama City University Medical Center, Minami-ku Urafune-chou 4-57, Yokohama, Kanagawa, 232-0024, Japan,
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