Document Detail


Successful treatment of permethrin toxicosis in two cats with an intravenous lipid administration.
MedLine Citation:
PMID:  22526817     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The present work describes successful treatment of permethrin toxicosis in two cats with a novel therapy of intravenous lipid administration. Two cats presented in lateral recumbency and with generalized tremor after they had been incidentally treated with permethrin for flea control by their owners. Initial therapy consisted of diazepam, propofol, bathing, and intravenous fluids. After an initial bolus of 2mg/kg BW pentobarbital a pentobarbital continuous rate infusion (CRI) was started. Both cats received an emulsion of 20% soybean oil and 80% olive oil, commonly used as fat component of total parenteral nutrition in humans, later in the course of therapy. A bolus of 2ml/kg BW of the emulsion followed by a CRI of 4ml/kg BW/h for 4 hours was administered via a jugular catheter as reported previously. One cat received two cycles of therapy with intravenous lipid whereas the other cat needed just one application. Both cats recovered completely without requiring any further treatment. In conclusion, administration of intravenous lipids for permethrin toxicosis in cats is a novel treatment approach which seems to be highly effective in shortening the recovery time for permethrin toxicosis and possibly other fat-soluble toxins.
Authors:
M Brückner; C S Schwedes
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere     Volume:  40     ISSN:  1434-1239     ISO Abbreviation:  Tierarztl Prax Ausg K Kleintiere Heimtiere     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-04-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9717383     Medline TA:  Tierarztl Prax Ausg K Kleintiere Heimtiere     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  129-34     Citation Subset:  IM    
Affiliation:
Michael Brückner, Tierärztliche Fachklinik für Kleintiere, Klinkerberg 1-3, 86152 Augsburg, E-Mail: MichaelBrueckner@gmx.de.
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