| Successful treatment of pediatric stroke with recombinant tissue plasminogen activator (rt-PA): a case report and review of the literature. | |
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MedLine Citation:
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PMID: 19000355 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pediatric stroke is a rare disorder with a paucity of evidence-based treatment options, and can result in significant morbidity and mortality. In contrast to adult acute ischemic stroke, where the use of recombinant tissue plasminogen activator (rt-PA) has been studied in several large, randomized clinical trials, no high-level evidence exists for the use of thrombolytics in children with stroke. We report a case of a 15-year-old girl who suffered an acute ischemic stroke and had a dramatic improvement in symptoms following the administration of intravenous rt-PA. |
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Authors:
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Shirra Cremer; Yaniv Berliner; David Warren; Andrew E Jones |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: CJEM Volume: 10 ISSN: 1481-8035 ISO Abbreviation: CJEM Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-11-12 Completed Date: 2009-03-19 Revised Date: 2011-10-05 |
Medline Journal Info:
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Nlm Unique ID: 100893237 Medline TA: CJEM Country: Canada |
Other Details:
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Languages: eng Pagination: 575-8 Citation Subset: IM |
Affiliation:
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Department of Biostatistics and Epidemiology, University of Western Ontario, London, Ontario, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adolescent Brain Ischemia / complications Causality Emergency Treatment / methods* Evidence-Based Emergency Medicine Female Fibrinolytic Agents / therapeutic use* Humans Infusions, Intravenous Injections, Intravenous Morbidity Pediatrics / methods* Practice Guidelines as Topic Randomized Controlled Trials as Topic Rare Diseases Stroke / drug therapy*, epidemiology, etiology Tissue Plasminogen Activator / therapeutic use* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Fibrinolytic Agents; EC 3.4.21.68/Tissue Plasminogen Activator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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