Document Detail

Successful treatment of a patient with primary Sjögren's syndrome complicated with pericarditis during pregnancy.
MedLine Citation:
PMID:  17634717     Owner:  NLM     Status:  MEDLINE    
A 35-year-old woman with primary Sjögren's syndrome (pSS) developed fever and chest pain during pregnancy. When the dose of prednisolone was reduced, she experienced chest pain with elevated CRP and D-dimer, resulting in admission to our hospital with marked cardiomegaly and pleural effusion. Because there was no evidence of other autoimmune disorders or infection, oral prednisolone was increased to 30 mg daily with heparin, and hypercoagulopathy was carefully monitored. The patient's condition improved rapidly, and she delivered a healthy baby. This is the first case to support the beneficial effect of prednisolone in pericarditis with pSS, and illustrates its safety during pregnancy.
Kazuo Mutsukura; Hideki Nakamura; Nozomi Iwanaga; Hiroaki Ida; Atsushi Kawakami; Tomoki Origuchi; Masako Furuyama; Katsumi Eguchi
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-07-17
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  46     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2007  
Date Detail:
Created Date:  2007-07-19     Completed Date:  2007-11-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1143-7     Citation Subset:  IM    
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki University.
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MeSH Terms
Glucocorticoids / therapeutic use
Pericarditis / complications*,  diagnosis,  therapy*
Prednisolone / therapeutic use
Pregnancy Complications / diagnosis,  therapy*
Pregnancy Outcome
Sjogren's Syndrome / complications*,  diagnosis,  therapy*
Treatment Outcome
Reg. No./Substance:
0/Glucocorticoids; 50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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