Document Detail

Successful treatment of paraneoplastic pemphigus in follicular NHL with rituximab: report of a case and review of treatment for paraneoplastic pemphigus in NHL and CLL.
MedLine Citation:
PMID:  11421295     Owner:  NLM     Status:  MEDLINE    
Paraneoplastic pemphigus is a severe mucocutaneous disease associated in most cases with B-cell lymphoproliferative disorders. Independent of the course of the underlying malignancy, this autoimmune skin disease is resistant to any treatment in most cases and may lead to death by infectious complications. We observed a patient with recovery of paraneoplastic pemphigus associated with follicular non-Hodgkin's-lymphoma after therapy with rituximab. In addition, we reviewed the literature and analyzed the few cases with comparable outcome with other treatment modalities.
M Heizmann; P Itin; M Wernli; L Borradori; M J Bargetzi
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  American journal of hematology     Volume:  66     ISSN:  0361-8609     ISO Abbreviation:  Am. J. Hematol.     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-06-25     Completed Date:  2001-07-19     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7610369     Medline TA:  Am J Hematol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  142-4     Citation Subset:  IM    
Center of Oncology, Hematology and Transfusion Medicine, Kantonsspital Aarau, Switzerland.
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MeSH Terms
Antibodies, Monoclonal / administration & dosage*
Antineoplastic Agents / administration & dosage
Leukemia, Lymphocytic, Chronic, B-Cell / complications,  drug therapy
Lymphoma / complications,  drug therapy
Lymphoma, Follicular / complications*,  drug therapy
Paraneoplastic Syndromes / drug therapy
Pemphigus / drug therapy*,  etiology
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Antineoplastic Agents; 0/rituximab

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