Document Detail

Successful treatment of late onset infection due to multi-drug resistant Acinetobacter Lwoffii in a low birth weight neonate using ciprofloxacin.
MedLine Citation:
PMID:  11556475     Owner:  NLM     Status:  MEDLINE    
This report presents the case of a low birth weight neonate with multidrug-resistant Acinetobacter Lwoffii infection who was successfully treated with ciprofloxacin and co-trimoxazole. Use of ciprofloxacin in pediatric populations was reviewed. The infant responded to the antibiotic regimen with sterilized cerebrospinal fluid with no adverse effects attributable to the ciprofloxacin. Although ciprofloxacin has been found to cause irreversible damage to cartilage in laboratory animals, a review of the literature found that this complication rarely occurs in pediatric patients. Ciprofloxacin has been found to be effective in the treatment of multidrug-resistant gram negative infections in pediatric patients, including premature infants. Ciprofloxacin should be considered in the treatment of neonatal infection caused by multidrug-resistant gram-negative organisms.
U Chotigeat; M Khorana; N Waranawat
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  84     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-09-14     Completed Date:  2001-10-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  910-3     Citation Subset:  IM    
Neonatal Unit, Queen Sirikit National Institute of Child Health, Bangkok, Thailand.
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MeSH Terms
Acinetobacter / drug effects
Acinetobacter Infections / drug therapy*
Anti-Infective Agents / pharmacology,  therapeutic use*
Ciprofloxacin / pharmacology,  therapeutic use*
Drug Resistance, Multiple
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / drug therapy*
Time Factors
Reg. No./Substance:
0/Anti-Infective Agents; 85721-33-1/Ciprofloxacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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