| Successful treatment of kasabach-merritt phenomenon with intralesional corticosteroid injections: a case series. | |
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MedLine Citation:
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PMID: 23154333 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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ABSTRACT: Kasabach-Merritt phenomenon (KMP) is a rare and life-threatening disease of vascular tumor combined with severe consumptive coagulopathy. Currently, there is no established effective treatment of KMP. In this case series, from 2006 to 2008, we treated 6 pediatric patients with newly diagnosed KMP using intralesional corticosteroid injections. The severity and progression of the disease were closely monitored with clinical photographs, blood sampling, and tissue biopsies. The 6 pediatric patients (5 females and 1 male) showed tumor regression after treatments. All coagulopathies were corrected. The average duration of treatment was 3.8 months. Complete tumor regression was observed at approximately 3 years. Treatment was complicated in 1 patient with transient growth retardation. Treatment based on intralesional corticosteroid injections is effective for pediatric patients with KMP. Treatment-associated complications seemed to be reversible and acceptable by severity level. |
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Authors:
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Jian-Jr Lee; Li-Ying Lin; Shun-Wen Hsieh; Ting-An Chang; Shiann-Tarng Jou; Charlos Chih-Ho Liu; Ming-Ting Chen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annals of plastic surgery Volume: 69 ISSN: 1536-3708 ISO Abbreviation: Ann Plast Surg Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-11-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7805336 Medline TA: Ann Plast Surg Country: United States |
Other Details:
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Languages: eng Pagination: 627-32 Citation Subset: IM |
Affiliation:
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From the *Division of Plastic Surgery, Department of Surgery, Cathay General Hospital; †Department of Pathology, Taipei Hospital, Department of Health; ‡Department of Pathology, Renai Branch of Taipei City Hospital; §Department of Pediatrics, National Taiwan University Hospital; ||Department of Computer Science and Information Engineering, National Taiwan University; and ¶Division of Plastic Surgery, Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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