Document Detail


Successful treatment of infertility due to anejaculation with in vitro fertilization and embryo transfer: a report of two cases.
MedLine Citation:
PMID:  9591339     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We investigated the efficacy of assisted ejaculation in combination with in vitro fertilization and embryo transfer (IVF-ET) in two couples with infertility due to anejaculation. Case 1 was in an anejaculatory condition associated with a spinal cord-injury. We performed intrauterine insemination (IUI) three times using motile sperm obtained by intrathecal injection of neostigmine, but no pregnancy followed. The couple then entered IVF-ET. The semen volume obtained by assisted ejaculation was 4.5 ml. The sperm count was 33 x 10(6)/ml with 33% motility. At 35 weeks of gestation she delivered three healthy babies by cesarean section. Case 2 was in an unexplained retrograde ejaculatory condition. We performed IUI eight times before changing to IVF-ET. We then used sperm obtained from urine or sperm recovered from the bladder after administration of human tubal fluid, but no pregnancy followed. At the fifth IVF-ET attempt, using sperm obtained from urine, we succeeded. We prepared the sperm by the Percoll gradient method. The sperm count was 36 x 10(6)/ml with 64% motility. At 39 weeks of gestation she delivered a healthy baby. Deficient seminal quality contributes to the decreased fertility potential in patients with anejaculation. With the use of IVF-ET methods, pregnancies can be achieved in these couples.
Authors:
S Nagai; T Kasai; K Ogawa; K Mizuno; S Ohta; K Hoshi
Related Documents :
25429089 - B cells in pregnancy: functional promiscuity or tailored function?
2497249 - Monitoring gonadotropin therapy.
20970129 - In vitro fertilization-intracytoplasmic sperm injection outcomes in single- versus doub...
11868629 - Treatment of sperm with subnormal host scores with chymotrypsin/viable pregnancy after ...
12798529 - Elevated sperm chromosome aneuploidy and apoptosis in patients with unexplained recurre...
12801569 - Efficacy and pregnancy outcome of two methods of semen preparation for intrauterine ins...
24770189 - Can fetal abdominal circumference at term predict shoulder dystocia?
15632339 - Urinary placental growth factor and risk of preeclampsia.
19939379 - Trends and determinants of pregnancy-related domestic violence in a referral center in ...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Tohoku journal of experimental medicine     Volume:  184     ISSN:  0040-8727     ISO Abbreviation:  Tohoku J. Exp. Med.     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1998-07-23     Completed Date:  1998-07-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417355     Medline TA:  Tohoku J Exp Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  241-6     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Yamanashi Medical University, Japan. seiichi@res.yamanashi-med.ac.jp
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Ejaculation*
Embryo Transfer / methods*
Female
Fertilization in Vitro / methods*
Humans
Infertility, Male / etiology,  therapy*
Male
Pregnancy
Spinal Cord Injuries / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Detection of the PGP9.5 and tyrosine hydroxylase mRNAs for minimal residual neuroblastoma cells in b...
Next Document:  Peripheral blood stem cell transplantation for hepatoblastoma with microscopical residue: a therapeu...