Document Detail

Successful treatment of hereditary factor VII deficiency presented for the first time with epistaxis in pregnancy: a case report.
MedLine Citation:
PMID:  20476876     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To present a rare case with factor VII deficiency (FVIID) that first diagnosed during pregnancy, and to disccuss the ante-, peri- and postpartum management.
STUDY DESIGN: A case report and review of the literature.
RESULTS: FVIID was diagnosed for the first time in a 23-year-old pregnant woman at the 24th week of gestation due to complaint of intermittent epistaxis. She was successfully treated by ante-, peripartum and postpartum replacement of recombinant FVII (rFVII). She was uneventfully discharged on the 3rd postoperative day and referred to hematology department for further follow-up.
CONCLUSION: FVIID, a rare cause of ante- and postpartum hemorrhages that may differently present by other hemorrhages (i.e.: epistaxis), can be optimally managed with replacement of rFVII.
Gülşah Aynaoğlu; Gülşen Doğan Durdağ; Batuhan Ozmen; Feride Söylemez
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  23     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-19     Completed Date:  2010-12-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  1053-5     Citation Subset:  IM    
Ankara University School of Medicine, Department of Obstetrics and Gynecology, Ankara, Turkey.
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MeSH Terms
Epistaxis / complications,  diagnosis,  therapy*
Factor VII / therapeutic use
Factor VII Deficiency / complications,  diagnosis,  genetics,  therapy*
Pregnancy Complications, Hematologic / diagnosis,  genetics,  therapy*
Recombinant Proteins / therapeutic use
Treatment Outcome
Young Adult
Reg. No./Substance:
0/Recombinant Proteins; 9001-25-6/Factor VII

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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