Document Detail

Successful treatment of eosinophilic pustular folliculitis with topical tacrolimus 0.1 percent ointment.
MedLine Citation:
PMID:  22398231     Owner:  NLM     Status:  MEDLINE    
Classic eosinophilic pustular folliculitis (EPF), otherwise known as Ofugi disease, is a rare condition commonly treated with topical glucocorticosteroids. If this fails, oral indomethacin is frequently the next line. Because the condition is recurrent, the use of long term steroids may cause side effects such as skin atrophy, hypertrichosis, and dyspigmentation. Topical tacrolimus is an immunosuppressant that is generally used as a steroid-sparing agent in atopic dermatitis. We report a case of classic EPF, which was recurrent over 5 years that had failed topical glucocorticosteroids but was successfully treated with topical tacrolimus 0.1 percent ointment.
Shanna Shan-Yi Ng; Yong-Kwang Tay
Publication Detail:
Type:  Journal Article     Date:  2012-02-15
Journal Detail:
Title:  Dermatology online journal     Volume:  18     ISSN:  1087-2108     ISO Abbreviation:  Dermatol. Online J.     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-03-08     Completed Date:  2012-07-17     Revised Date:  2012-10-04    
Medline Journal Info:
Nlm Unique ID:  9610776     Medline TA:  Dermatol Online J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  10     Citation Subset:  IM    
Department of Dermatology, Changi General Hospital, Singapore.
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MeSH Terms
Eosinophilia / diagnosis,  drug therapy*,  pathology
Folliculitis / diagnosis,  drug therapy*,  pathology
Glucocorticoids / therapeutic use
Immunosuppressive Agents / therapeutic use*
Indomethacin / therapeutic use
Middle Aged
Ointments / therapeutic use
Skin Diseases, Vesiculobullous / diagnosis,  drug therapy*,  pathology
Tacrolimus / therapeutic use*
Treatment Outcome
Reg. No./Substance:
0/Glucocorticoids; 0/Immunosuppressive Agents; 0/Ointments; 109581-93-3/Tacrolimus; 53-86-1/Indomethacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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