| Successful treatment of distal coronary guidewire-induced perforation with balloon catheter delivery of intracoronary thrombin. | |
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MedLine Citation:
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PMID: 12594705 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Distal coronary artery perforation with a coronary guidewire is a relatively rare but potentially fatal complication during PTCA. Historically, these types of perforations have been easy to control with reversal of heparin anticoagulation combined with prolonged distal balloon inflation. In the modern era, with widespread use of potent glycoprotein IIb/IIIa inhibitors, this type of distal wire perforation has become more difficult to manage and potentially lethal. In this article, we report two cases of guidewire-related distal coronary artery perforation, successfully treated using a new technique using localized, distal intracoronary thrombin injection. During prolonged low-pressure balloon inflation, a small dose of thrombin was injected just proximal to the wire perforation site via the lumen of a coronary balloon catheter. This approach appears to be a relatively rapid and effective way to control this troublesome complication. |
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Authors:
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Tim A Fischell; Elie H Korban; Michael A Lauer |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions Volume: 58 ISSN: 1522-1946 ISO Abbreviation: Catheter Cardiovasc Interv Publication Date: 2003 Mar |
Date Detail:
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Created Date: 2003-02-20 Completed Date: 2003-06-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 100884139 Medline TA: Catheter Cardiovasc Interv Country: United States |
Other Details:
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Languages: eng Pagination: 370-4 Citation Subset: IM |
Copyright Information:
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Copyright 2003 Wiley-Liss, Inc. |
Affiliation:
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Department of Medicine, Michigan State University, Kalamazoo, Michigan 49048, USA. taf1@net-link.net |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Angioplasty, Transluminal, Percutaneous Coronary / adverse effects* Balloon Dilatation / methods* Coronary Angiography Coronary Vessels / injuries* Female Heart Injuries / etiology*, radiography, therapy* Hemostatics / administration & dosage*, therapeutic use* Humans Injections, Intralesional / methods* Intraoperative Complications* Male Thrombin / administration & dosage*, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Hemostatics; EC 3.4.21.5/Thrombin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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