Document Detail


Successful treatment of cytomegalovirus polyradiculopathy in a 9-year-old child with congenital human immunodeficiency virus infection.
MedLine Citation:
PMID:  19182160     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cytomegalovirus lumbosacral polyradiculopathy is a well-documented complication of human immunodeficiency virus in adults who have a CD4 count of less than 40/microL. Patients present with an acute ascending flaccid paralysis of the lower limbs with areflexia, paresthesia, and urinary and bowel symptoms. However, it appears to be rare in children with congenitally acquired immune deficiency syndrome. We report a 9-year-old child with congenital human immunodeficiency virus infection who presented with cytomegalovirus polyradiculopathy and made an excellent response to cytomegalovirus treatment.
Authors:
Aman Sohal; Andrew Riordan; Mac Mallewa; Tom Solomon; Rachel Kneen
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of child neurology     Volume:  24     ISSN:  1708-8283     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-02     Completed Date:  2009-05-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  215-8     Citation Subset:  IM    
Affiliation:
Department of Neurology, Littlewoods Neuroscience Foundation, Royal Liverpool Children's NHS Trust, Alder Hey, Liverpool, United Kingdom.
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MeSH Terms
Descriptor/Qualifier:
AIDS-Related Opportunistic Infections / drug therapy*,  pathology
Antiviral Agents / therapeutic use*
Brain / pathology
Child
Cytomegalovirus Infections / drug therapy*,  pathology
Drug Therapy, Combination
Female
Foscarnet / therapeutic use
Ganciclovir / therapeutic use
HIV Infections / congenital*
Humans
Magnetic Resonance Imaging
Polyradiculopathy / drug therapy*,  pathology,  virology
Spine / pathology
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antiviral Agents; 4428-95-9/Foscarnet; 82410-32-0/Ganciclovir

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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