| Successful treatment of atrophic postoperative and traumatic scarring with carbon dioxide ablative fractional resurfacing: quantitative volumetric scar improvement. | |
| | |
MedLine Citation:
|
PMID: 20157023 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To assess the safety and efficacy of ablative fractional resurfacing (AFR) for nonacne atrophic scarring. DESIGN: In this before-and-after trial, each scar received 3 AFR treatments and 6 months of follow-up. SETTING: Private academic practice. PATIENTS: Fifteen women with Fitzpatrick skin types I to IV, aged 21 to 66 years, presented with 22 nonacne atrophic scars between June 1 and November 30, 2007. Three patients (3 scars) were excluded from the study after receiving 1 AFR treatment and not returning for follow-up visits. The remaining 12 patients (19 scars) completed all 3 treatments and 6 months of follow-up. INTERVENTIONS: Each scar received 3 AFR treatments at 1- to 4-month intervals. MAIN OUTCOME MEASURES: Erythema, edema, petechiae, scarring, crusting, and dyschromia were graded after treatment and through 6 months of follow-up. Skin texture, pigmentation, atrophy, and overall appearance were evaluated after treatment and through 6 months of follow-up by the patient and a nonblinded investigator. A 3-dimensional optical profiling system generated high-resolution topographic representations of atrophic scars for objective measurement of changes in scar volume and depth. RESULTS: Adverse effects of treatment were mild to moderate, and no scarring or delayed-onset hypopigmentation was observed. At the 6-month follow-up visit, patient and investigator scores demonstrated improvements in skin texture for all scars (patient range, 1-4 [mean, 2.79]; investigator range, 2-4 [mean, 2.95]), pigmentation for all scars (patient range, 1-4 [mean, 2.32]; investigator range, 1-4 [mean, 2.21]), atrophy for all scars (patient range, 1-4 [mean, 2.26]; investigator range, 2-4 [mean, 2.95]), and overall scar appearance for all scars (patient range, 2-4 [mean, 2.89]; investigator range, 2-4 [mean, 3.05]). Image analysis revealed a 38.0% mean reduction of volume and 35.6% mean reduction of maximum scar depth. CONCLUSION: The AFR treatments represent a safe, effective treatment modality for improving atrophic scarring due to surgery or trauma. |
| | |
Authors:
|
Elliot T Weiss; Anne Chapas; Lori Brightman; Christopher Hunzeker; Elizabeth K Hale; Julie K Karen; Leonard Bernstein; Roy G Geronemus |
Related Documents
:
|
14726733 - Combination of surgery and intralesional verapamil injection in the treatment of the ke... 22269293 - Helicobacter pylori eradication improves gastric atrophy and intestinal metaplasia in l... 11951063 - Side clamp used during off-pump coronary artery bypass does not increase the risk of st... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Archives of dermatology Volume: 146 ISSN: 1538-3652 ISO Abbreviation: Arch Dermatol Publication Date: 2010 Feb |
Date Detail:
|
Created Date: 2010-02-16 Completed Date: 2010-03-23 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0372433 Medline TA: Arch Dermatol Country: United States |
Other Details:
|
Languages: eng Pagination: 133-40 Citation Subset: AIM; IM |
Affiliation:
|
Laser & Skin Surgery Center of New York, 317 E 34th St, New York, NY 10016, USA. eweiss@laserskinsurgery.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Atrophy / etiology, pathology, surgery Cicatrix / etiology, pathology*, surgery* Face Female Follow-Up Studies Humans Laser Therapy / methods* Lasers, Gas / therapeutic use* Male Middle Aged Postoperative Complications* Prospective Studies Treatment Outcome Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Extent and clinical consequences of antibody formation against adalimumab in patients with plaque ps...
Next Document: Modern moulage: evaluating the use of 3-dimensional prosthetic mimics in a dermatology teaching prog...