Document Detail


Successful treatment of anisometropic amblyopia with spectacles alone.
MedLine Citation:
PMID:  16527678     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The efficacy of treating anisometropic amblyopia with occlusion therapy is well known. However, this form of treatment can be associated with risks. Spectacle correction alone may be a successful and underutilized form of treatment. METHODS: The records of 28 patients treated successfully for anisometropic amblyopia with glasses alone were reviewed. Age, initial visual acuity and stereoacuity, and nature of anisometropia were analyzed to assess associations with time required for resolution, final visual acuity, and stereoacuity. Incidence of amblyopia recurrence and results of subsequent treatment, including patching, were also studied. RESULTS: Mean time to amblyopia resolution (interocular acuity difference <or=1 line) was 5.8 months (range 2 to 15 months). Worse best corrected initial visual acuity was associated with longer time to resolution (Spearman's rho = 0.37, P = 0.05), while age, initial stereoacuity, amount, and type of anisometropia were not (P = 0.43, 0.68, 0.26, 0.47, respectively). None of the astigmatic or myopic patients achieved visual acuity of 20/20 in the amblyopic eye, while seven (39%) of the hyperopic patients did. This difference was significant (P = 0.03). Better initial stereoacuity predicted good final stereoacuity (P = 0.01). Only four (14%) patients developed amblyopia recurrence over an average follow-up period of 1.7 years. All were successfully treated with updated spectacles or patching. CONCLUSIONS: Treatment of anisometropic amblyopia with spectacles alone can be a successful option. Patients treated with spectacles alone may experience a lower amblyopia recurrence rate than those treated with occlusion therapy.
Authors:
Anna L Steele; Yasmin S Bradfield; Burton J Kushner; Thomas D France; Michael C Struck; Ronald E Gangnon
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus     Volume:  10     ISSN:  1091-8531     ISO Abbreviation:  J AAPOS     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-03-10     Completed Date:  2006-04-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9710011     Medline TA:  J AAPOS     Country:  United States    
Other Details:
Languages:  eng     Pagination:  37-43     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, University of Wisconsin, Madison, USA.
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MeSH Terms
Descriptor/Qualifier:
Amblyopia / physiopathology,  therapy*
Anisometropia / physiopathology,  therapy*
Child
Child, Preschool
Eyeglasses*
Female
Follow-Up Studies
Humans
Infant
Male
Recurrence
Retrospective Studies
Treatment Outcome
Vision, Binocular / physiology
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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