| Successful treatment of angiofibromata of tuberous sclerosis complex with rapamycin. | |
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MedLine Citation:
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PMID: 20673154 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Abstract Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous syndrome manifesting as hamartomatous growths in multiple organs. We present two cases of patients with TSC and associated facial angiofibromata treated with topical and oral rapamycin and discuss the role for rapamycin in the treatment of these disfiguring lesions. Our patients demonstrated decreased numbers of angiofibromata and less redness with this treatment. This is the first published report on the use of topical rapamycin for the treatment of angiofibromata. |
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Authors:
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Elizabeth Kaufman McNamara; Ashley R Curtis; Alan B Fleischer |
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Publication Detail:
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Type: Journal Article Date: 2010-08-01 |
Journal Detail:
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Title: The Journal of dermatological treatment Volume: 23 ISSN: 1471-1753 ISO Abbreviation: J Dermatolog Treat Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-01-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8918133 Medline TA: J Dermatolog Treat Country: England |
Other Details:
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Languages: eng Pagination: 46-8 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Wake Forest University School of Medicine , Winston-Salem, North Carolina , USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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