| Successful treatment of advanced interstitial pregnancy with methotrexate and hysteroscopy. A case report. | |
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MedLine Citation:
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PMID: 9749430 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Data concerning medical treatment of interstitial ectopic pregnancies are scarce. These pregnancies are characterized by late and serious clinical manifestations. We report a case of advanced interstitial pregnancy treated successfully by combining methotrexate (MTX) and hysteroscopy. CASE: A routine ultrasonic evaluation of a 10-week pregnancy revealed a right interstitial gestational sac 58 mm in diameter and containing an embryo with a crownrump length of 29 mm and embryonic heartbeats. Serum beta-human chorionic gonadatropin (hCG) level was 97,950 mIU/mL. The patient was treated with a systemic MTX/leucovorin regimen. At the end of the one-week course, no embryonic cardiac activity was detected, and a decrease in beta-hCG levels commenced. Persistent trophoblastic tissue, manifested by a low (26 mIU/mL) beta-hCG level in plateau, was successfully removed by way of hysteroscopy. CONCLUSION: Early detection of interstitial pregnancy may facilitate conservative medical treatment. |
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Authors:
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A Groutz; Y Wolf; B Caspi; I Wolman; D Gordon; M P David |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of reproductive medicine Volume: 43 ISSN: 0024-7758 ISO Abbreviation: J Reprod Med Publication Date: 1998 Aug |
Date Detail:
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Created Date: 1998-12-08 Completed Date: 1998-12-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0173343 Medline TA: J Reprod Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 719-22 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, LisSerlin Maternity Hospital, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortifacient Agents, Nonsteroidal
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therapeutic use* Adult Antidotes / therapeutic use Endoscopy* Fallopian Tubes / pathology, surgery Female Humans Hysteroscopy* Leucovorin / therapeutic use Methotrexate / therapeutic use* Pregnancy Pregnancy, Ectopic / therapy*, ultrasonography Uterus / pathology, surgery |
| Chemical | |
Reg. No./Substance:
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0/Abortifacient Agents, Nonsteroidal; 0/Antidotes; 58-05-9/Leucovorin; 59-05-2/Methotrexate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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